Functional treatment of snoring based on the tongue-repositioning manoeuvre.

Orofacial biofunction comprises muscular and physical effects, which may contribute to stabilization of the oropharyngeal airway. The tongue-repositioning manoeuvre (TRM) provides physical stabilization of the tongue and the soft palate together with, as a prerequisite, a nasal breathing mode. The aim of the present study was to evaluate the influence of a TRM treatment concept on primary snoring.

Comparative evaluation of D-dimer assays for exclusion of deep venous thrombosis in symptomatic outpatients.

Diagnostic work-up of patients sent to the hospital for diagnosing of deep venous thrombosis (DVT) often combines the determination of D-dimer and the application of a clinical probability score. To fulfill diagnostic as well as economic needs, D-dimer assays should exhibit a high negative predictive value (NPV) as well as reasonable specificity. In this study, we evaluated both a latex-enhanced immunoassay for use on routine coagulation analyzers and a radial partition immunoassay (RPIA) for use on a point-of-care analyzer.