- The study compared the effectiveness of one sample FIT (1-FIT) versus two sample FIT (2-FIT) screenings for colorectal cancer over four rounds, focusing on participation, positive predictive value, and diagnostic yield.
- A population-based sample of asymptomatic individuals aged 50-74 in the Netherlands was invited to participate, with data collected from those who completed at least one round of screening over a nine-year period.
- Results showed that participation rates were slightly higher for 1-FIT (74.7%) compared to 2-FIT (72.5%), indicating a preference for the single sample test among invitees.