Publications by authors named "Wolf-Dieter Reinbold"
Article Synopsis
- The enzyme MGMT is crucial for DNA repair by removing harmful methyl groups from DNA, and researchers identified a genetic variation (SNP rs12917) near its active site in Hodgkin lymphoma (HL) cell lines and patients.
- The study analyzed the presence of this SNP in five HL cell lines and 29 pediatric HL patients, examining its correlation with factors like age, gender, and treatment response.
- Findings revealed that the minor T allele was present in some cell lines and patients, with those carrying the C allele showing better metabolic responses to treatment and fewer needing radiation therapy, suggesting that this polymorphism could influence treatment outcomes in pediatric HL.
Background: Perisellar infiltration may be responsible for incomplete removal of pituitary tumors. Since intraoperative visualization of parasellar structures is difficult during transsphenoidal surgery, we are describing the use of intraoperative direct contact ultrasound (IOUS).
Methods: Within 5 years, in 113 transsphenoidal operations (58 male, 55 female, age 14-81 years, 110 pituitary adenomas (mean diameter 26.
Primary leptomeningeal melanocytic tumors (PLMTs) are rare. They usually arise along the spinal cord and at the skull base. Here we report on a patient with a very rare intraventricular melanocytoma.
View Article and Find Full Text PDFBackground: The diagnosis of Cushing disease is based on endocrinological pa-rameters, with no single test being specific. In some patients, dynamic thin-slice sellar magnetic resonance imaging fails to detect a pituitary tumor.
Objective: The purpose of this study is to investigate the role of ectopic pituitary adenoma in this situation.