Publications by authors named "Wolf H Schunck"
Article Synopsis
- Long-term parenteral nutrition can cause liver disease in patients, but omega-3 fatty acids like EPA and DHA may help prevent this condition.* -
- In a study with 8 patients, researchers observed changes in fatty acid profiles and metabolites after adding fish oil to parenteral nutrition for 8 weeks, which significantly increased omega-3 levels.* -
- The results showed that fish oil primarily increases inflammation-reducing compounds from EPA and DHA without causing significant changes in inflammation or liver function over the short study period.*
Obesity is often accompanied by metabolic and haemodynamic disorders such as hypertension, even during childhood. Arachidonic acid (AA) is metabolized by cytochrome P450 (CYP450) enzymes to epoxyeicosatrienoic acids (EETs) and 20-hydroxyeicosatetraenoic acid (20-HETE), vasoactive and natriuretic metabolites that contribute to blood pressure (BP) regulation. Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) omega-3 polyunsaturated fatty acids may compete with AA for CYP450-dependent bioactive lipid mediator formation.
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