Publications by authors named "Wojtek Swiatek"
Proc Natl Acad Sci U S A
September 2007
Article Synopsis
- The metabolic syndrome, linked to obesity and diabetes, poses a major global health risk due to improper cellular metabolic sensing.
- Research on PASK(-/-) mice reveals that the deletion of PAS kinase leads to specific metabolic changes, such as poor insulin secretion from pancreatic cells and altered fat storage in the liver.
- These mice show significant protection from the negative impacts of a high-fat diet, suggesting that PASK may help regulate cellular energy balance and could be a potential target for treating metabolic diseases.
