Gadopiclenol is a new gadolinium-based contrast agent with higher effectiveness that may allow for a lower dose compared to standard agents like gadobutrol, making it potentially safer.
A study involving 273 adults evaluated whether gadopiclenol at a lower dose (0.05 mmol/kg) is as effective as gadobutrol at a standard dose (0.1 mmol/kg) for imaging lesions in various body regions using MRI.
The results showed that gadopiclenol performed equally well as gadobutrol in visualizing lesions, with 75% to 83% of readers showing no preference for one over the other, and both agents had similar safety profiles regarding adverse events.
According to the literature, skin metastases affect 0.7%-10.4% of patients with malignant neoplasms of internal organs and may be 1 presentation of systemic spread of the cancer.