Ozone therapy in induced endotoxemic shock. II. The effect of ozone therapy upon selected histochemical reactions in organs of rats in endotoxemic shock.

Mitochondria and lysosomes were evaluated by assessment of changes in activity of selected enzymes: lactate dehydrogenase (LDH), succinate dehydrogenase (SDH), adenosinetriphosphatase (ATPase), acid phosphatase (AcPase) and beta-glucuronidase (BG) in rats under profound hypoxia induced by endotoxemic shock. The study was conducted on adult male Wistar rats. The animals formed the following four groups of 15 rats each: control animals (C);-rats receiving intraperitonally O(2)/O(3) (CO), rats receiving of Escherichia coli toxin (LPS) (CL); rats receiving LPS plus oxygen-ozone mixture (OL).

[Analysis of leptin pulses in serum in women with polycystic ovary syndrome].

Objectives: Authors estimate the influence of body mass on the leptin serum concentrations changes in course of 24 hours in twelve women with polycystic ovary syndrome (PCOS).

Material And Methods: The course of leptin pulses was analysed in two volunteers' six-persons groups, both with PCOS. first group with BMI < 22 kg/m2 and the second group with BMI >26 kg/m2.

[Detection methods of diurnal changes in plasma leptin concentrations].

Objectives: The authors evaluated the usefulness of the three mathematical methods used to identify pulses in the diurnal rhythm of leptin concentration variations in blood serum.

Design: In order to perform the evaluation 160 cases of computer-aided pulse simulation were used. Also the evaluation of leptin concentration variations in 2 healthy women (lean and obese) was made.