Publications by authors named "Wojciech Kmiecik"

Article Synopsis
  • Chronic nonbacterial osteomyelitis (CNO) is an autoinflammatory bone disease primarily found in children and adolescents, and sacroiliitis is an inflammatory condition of the sacroiliac joint diagnosed via MRI.
  • A case study details a 17.5-year-old female patient with classical Ehlers-Danlos syndrome (EDS) who experienced joint pain, hypermobility, and morning stiffness, leading to the diagnosis of CNO and sacroiliitis after a whole-body MRI revealed inflammation.
  • The patient was successfully treated with a combination of medications including risedronate sodium and methotrexate, achieving remission, highlighting the importance of interdisciplinary cooperation for managing the overlapping conditions.
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Article Synopsis
  • MRI is increasingly used to diagnose conditions related to juvenile idiopathic arthritis and other rheumatic diseases in children, focusing on detecting changes in joints and surrounding tissues.
  • Various MRI techniques, such as T1, T2, and STIR sequences, are used to identify issues like synovitis and bone marrow edema.
  • Pediatric-specific MRI scoring systems help standardize assessments of inflammation and disease activity, enabling early treatment and potential for remission.
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The Bacillus Calmette-Guérin (BCG) vaccine has been in use for over 100 years. It protects against severe, blood-borne forms of tuberculosis. Observations indicate that it also increases immunity against other diseases.

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Tuberculosis (TB) was the predominant cause of death from a single infectious agent worldwide before the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) pandemic. Although TB vaccines have been successfully used for about 100 years, their full effect is still unknown. In previous studies, a reduced incidence and mortality from a coronavirus disease in TB-vaccinated populations were reported.

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Tuberculosis vaccines (Bacillus Calmette-Guérin, BCG) were introduced 100 years ago and are still recommended by the World Health Organization to prevent the disease. Studies have shown that BCG vaccination can stimulate non-specific immune responses and reduce the incidence of certain diseases. At the beginning of the coronavirus disease 2019 (COVID-19) pandemic, it was hypothesised that the incidence of COVID-19 was lower in countries with BCG prevention.

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