[Prevention of thromboembolism in para-articular femoral fractures of the hip--results of a prospective randomized study of heparin-DHE and ASS-DHE].

The effectiveness of prophylaxis of thromboembolism either by acetyl-salicylic-acid (ASA) 0.5 g + dihydroergotamin (DHE) 2.5 mg three times a day or by Heparin 5000 IU + 0.

[The efficacy of cytoplasmatic therapy in elderly patients].

It has been studied whether cytoplasmatic therapy with macromolecular substances can favourably influence symptoms of the progressive aging process in old patients. For this purpose a randomized double-blind study was carried out in a geriatric clinic. A marked and statistically significant improvement was observed in the patients after four weeks real treatment as compared with the placebo group, using as criteria the ECG, the frequency of cerebral symptoms and the result of psychological tests.

[Controlled randomized double-blind study for the comparison of the treatment of patients with essential hypertension with homeopathic and with pharmacologically effective drugs].

In a randomized double-blind cross-over study the effects of antihypertensive pharmacotherapy were compared with those of homeopathic treatment in 10 patients with essential hypertension. The conclusions are: 1. The blood pressure lowering effect under pharmacotherapy is clearly superior to that under homeotherapy, where it was negligible and statistically not significant.

[Timolol in the treatment of glaucoma (author's transl)].

Untolerated or insufficiently effective Therapy in 32 patients (63 eyes) with primary open-angle glaucoma was discontinued and substituted with Timolol, and all patients were followed up over a period of 60 weeks. Timolol was well tolerated in all cases without any local or systemic side effects. Either alone or in combination with other medications Timolol brought about an adequate reduction in intraocular pressure in eyes which hitherto had no longer responded to conventional conservative therapy.

[Anticholinergic drugs in open-angle glaucoma (author's transl)].

The widespread uncertainty as to whether anticholinergic drugs are contra-indicated in cases of open-angle glaucoma led us to investigate the influence of such a drug on intraocular pressure. In an earlier publication we stated that Pizotifen may be used in treated open-angle glaucoma, it does not crucially impair conservative local antiglaucoma treatment. We have now examined its influence on pressure in untreated glaucomatous eyes and have found that patients with untreated open-angle glaucoma may also be treated with 2.

[Influence of anticholinergic drugs on the intraocular tension of medicinally treated glaucoma simplex (author's transl)].

In 10 patients the influence of pizotifen on the intraocular tension of their medicinally treated open-angle glaucoma was examined. The clinical results and their statistical evaluation showed that anticholinergic drugs behaving pharmacologically like pizotifen do not impair conservative antiglaucomatous local treatment. Therefore, they may be used in cases of open-angle glaucoma.

Analysis of a certain type of 2 x 3 tables, exemplified by biopsy findings in a controlled clinical trial.

A procedure is described for the evaluation of 2 X 3 Tables, in which the two rows correspond to the two treatments to be compared and the three columns are ordered classifications ("improved", "unchanged", "deteriorated"). The method is illustrated by an example taken from the recent literature: liver biopsy data from a controlled clinical trial of silymarin in the treatment of chronic hepatitis.

[Determining the average posteruptive age of teeth from the results of cross-sectional studies (author's transl)].

If results of cross-sectional studies must be used as a basis for setting up models of development of caries in permanent teeth, then the average rather than individual posteruptive age of teeth has to be resorted to. Data available for this purpose had been obtained from a total of 54,000 children living in two G.D.

[Changes in glucose tolerance, serum insulin and blood lipids during contraceptive medication (oestrogen-gestagen) in metabolically-healthy women (author's transl)].

A low-dosage combination type of contraceptive (oestrogen-gestagen) was given to 19 metabolically- healthy women of normal weight over a period of 6 months. Glucose tolerance, serum insulin and serum lipids were measured 1 month before, during and 2 months after medication. There was a slight decrease in the basal insulin values and an opposite trend in the basal blood glucose values, not exceeding 10 mg% in comparison to pretreatment values.

Distribution of caries among tooth types in fluoride and non-fluoride areas.

A method is described for estimating the preferential caries protective action of fluoride on certain morphological types of permanent teeth. The results of an analysis by this method, applied to data for 1164 Austrian school-children aged 6--14 years, are reported. There was no indication that fluoride would exert its caries inhibitory effect selectively on certain types of teeth.