Use of asthma drugs and prevalence of molar incisor hypomineralization.

Background: Asthma and molar incisor hypomineralization (MIH) are common diseases among children and have been suspected to be associated with each other.

Aim: To examine the association between asthma or the use of asthma drugs and the prevalence of MIH.

Design: In a population-based cross-sectional study, we recorded MIH in 9-year-old children in Aalborg Municipality, Denmark, born in the year 2000.

Oral health-related quality of life among survivors of childhood cancer.

BACKGROUND. Childhood cancer survivors may have experienced a high number of invasive medical and dental procedures, which may affect their oral health-related quality of life (OHRQoL). AIM.

Association between use of asthma drugs and prevalence of demarcated opacities in permanent first molars in 6-to-8-year-old Danish children.

Objectives: Demarcated opacities in permanent first molars are common developmental tooth defects, characterized by areas with insufficient mineralization of the enamel. The defects present clinically as a continuum from creamy-white demarcated opacities, yellowish-brown demarcated opacities to macroscopic loss of tooth substance. The etiology is sparsely elucidated, but asthma drugs have been suspected to increase the prevalence.

Maternal use of oral contraceptives during early pregnancy and risk of hypospadias in male offspring.

Objectives: To examine the association between maternal use of oral contraceptives in early pregnancy and increased prevalence of hypospadias in male offspring.

Methods: We conducted a nationwide population-based case-control study using data from nationwide medical databases. Among live male births between January 1, 1996, and December 31, 2005, we identified all cases of hypospadias recorded anytime postpartum (n = 1683) and randomly selected 10 controls per case without such a diagnosis (n = 15 650), matched by year and hospital of birth.

Development of Danish version of child oral-health-related quality of life questionnaires (CPQ8-10 and CPQ11-14).

Background: The Child Perceptions Questionnaire (CPQ) is a self-reported questionnaire developed to measure oral health-related quality of life in children. The CPQ aims to improve the description of children's oral health, while taking into consideration the importance of psychological aspects in the concept of health. The CPQ exists in two versions: the CPQ8-10 for children aged 8-10 years and the CPQ11-14 for those aged 11-14 years.

Dental anxiety among survivors of childhood cancer: a cross-sectional study.

Background: Childhood cancer survivors may have experienced a high number of invasive medical and dental procedures which are known to be risk factors for dental anxiety.

Aim: The aim of this study was to examine the prevalence of dental anxiety among children who have survived cancer.

Design: In a cross-sectional study, we examined 51 6- to 14-year-old children who had been treated for cancer at Aalborg Hospital, and 192 children without cancer.

The incidence of interstitial lung disease 1995-2005: a Danish nationwide population-based study.

Background: Current data on incidence of interstitial lung diseases (ILDs) are sparse and concerns about an increasing trend have been raised. We examined incidence rates (IRs) of ILDs and changes in IRs between 1995 and 2005.

Methods: All persons with a first-time hospital discharge or outpatient diagnosis of ILD were identified through the Danish National Registry of Patients, which covers all Danish hospitals.

Prevalence and distribution of demarcated opacities in permanent 1st molars and incisors in 6 to 8-year-old Danish children.

Objective: To estimate the prevalence and describe the distribution of demarcated opacities and possible consequences of this condition in permanent 1st molars and incisors in Danish children.

Material And Methods: Among all 6 to 8-year-old children in two municipalities, 745 (83.6%) were clinically examined for the occurrence of creamy-white or yellowish-brown demarcated opacities, posteruptive breakdown of tooth substance in relation to the opacities, atypical restorations, and extractions, i.

A population-based observational study of dental caries among survivors of childhood cancer.

Background: The few published studies on caries among childhood cancer survivors are small and their results are conflicting. The study aim was to examine the risk of dental caries among children who have survived cancer.

Procedure: We included 299,426 7-year-old, 313,461 12-year-old, and 301,930 15-year-old children born between 1984 and 1988 in a nationwide population-based study linking records from Danish Cancer Registry with records from the national database on oral health.

Comorbidity and ovarian cancer survival in Denmark, 1995-2005: a population-based cohort study.

The impact of comorbid diseases on ovarian cancer survival is largely unknown. We therefore examined (i) the prevalence of comorbidity among ovarian cancer patients and (ii) the impact of comorbidity on ovarian cancer survival and mortality. Using hospital discharge data, we identified Danish women diagnosed with ovarian cancer between 1995 and 2005 (n= 1995 within a population of 1.

Trends in colorectal cancer survival in northern Denmark: 1985-2004.

Objective: The prognosis for colorectal cancer (CRC) is less favourable in Denmark than in neighbouring countries. To improve cancer treatment in Denmark, a National Cancer Plan was proposed in 2000. We conducted this population-based study to monitor recent trends in CRC survival and mortality in four Danish counties.

Maternal use of oral contraceptives and risk of hypospadias - a population-based case-control study.

The aim of this population-based case-control study was to examine the risk of isolated hypospadias in boys born to mothers who have used oral contraceptives in early pregnancy. The study was based on data from the Hungarian Case-Control Surveillance of Congenital Abnormalities from 1980 to 1996, and included 3,038 boys with hypospadias (cases), 24,799 boys without congenital abnormalities (CA-free controls), and 11,881 boys with abnormalities other than hypospadias. We used unconditional logistic regression to adjust for birth order, maternal age, maternal employment status, maternal diabetes, and pre-eclampsia.

Maternal use of selective serotonin reuptake inhibitors and risk of congenital malformations.

Background: Human data on the teratogenicity of selective serotonin reuptake inhibitors (SSRIs) are limited. We examined the association between SSRI use during early pregnancy and the risk of congenital malformations in the offspring.

Methods: In a population-based cohort study from Denmark, we identified 1051 women who filled prescriptions for SSRIs from 30 days before conception to the end of the first trimester; of those, 453 filled the prescription during the second or third pregnancy month.

Associations between dental anxiety, dental treatment due to toothache, and missed dental appointments among six to eight-year-old Danish children: a cross-sectional study.

The aims of this study were to estimate the prevalence of missed dental appointments among Danish children at 6 to 8 years of age and to examine the association between dental anxiety, dental treatment due to toothache, and missed dental appointments in a population-based cross-sectional study. The study was conducted in four municipalities in the County of North Jutland, Denmark, and included a total of 1,235 children (response rate 74.1%).

Further analysis of the risk of adverse birth outcome after maternal use of fluoroquinolones.

In a database cohort study, the risk of adverse birth outcome in Danish women who redeemed a fluoroquinolone prescription during pregnancy was examined. Among 87 women who redeemed a fluoroquinolone prescription at any time during the pregnancy, the prevalence ratio of preterm birth was 1.4 (95% confidence interval (CI), 0.

Validity of parental-reported questionnaire data on Danish children's use of asthma-drugs: a comparison with a population-based prescription database.

The aim of this study was to examine the validity--estimated as the sensitivity, specificity, and predictive values--of questionnaire-based parental reporting on Danish children's use of asthma drugs. Within a population-based cross-sectional study on the association between asthma and dental anxiety, we compared parental answers on their children's use of asthma drugs during the past 12 months with National Health Service (NHS) data from a prescription database on prescriptions of inhaled beta 2-agonists, inhaled corticosteroids, or both for a period of 14 months preceding the date of posting the parental questionnaires. In four municipalities in North Jutland County, Denmark, in 2001, parents of 1273 children between the ages of 6 and 8 years completed the questionnaire.

Use of asthma-drugs and risk of dental caries among 5 to 7 year old Danish children: a cohort study.

Objective: To estimate the risk of dental caries in 5-7 year old Danish children who received prescriptions for asthma-drugs.

Design: Population-based cohort-study based on data from a prescription registry and dental database. Setting The County of North Jutland, Denmark.

Asthma, ear problems, and dental anxiety among 6- to 8-yr-olds in Denmark: a population-based cross-sectional study.

The aim of this study was to examine the association between asthma, ear problems, and dental anxiety in children in a population-based cross-sectional study. The population included four municipalities in the County of North Jutland, Denmark, in 2001. A total of 1235 children aged 6-8 yr, and their parents, were identified.

Prevalence of dental anxiety and behavior management problems among six to eight years old Danish children.

The aim of this study was to estimate the prevalence of dental anxiety among 6 to 8-year-old Danish children using the Children's Fear Survey Schedule-Dental Subscale (CFSS-DS) and behavior management problems. The study was designed as a population-based cross-sectional survey of children attending the municipal dental service in four municipalities in the county of North Jutland, Denmark. In 2001, the CFSS-DS questionnaire was mailed to the parents of all children born in 1993, 1994, and 1995 (parents of 1666 children) in 4 municipalities.