Publications by authors named "Woerdt A"

Article Synopsis
  • The study aimed to find genetic links to primary glaucoma (PG) in American Cocker Spaniels through a genome-wide association study (GWAS).
  • Ninety-four PG-affected dogs and 111 healthy controls underwent genomic analysis after veterinary examinations and owner consent, with blood samples collected for DNA extraction.
  • The results indicated a potential association with a specific area on canine chromosome 10, involving candidate genes CCDC85A and EFEMP1, which are also relevant to human glaucoma, though the findings did not achieve statistical significance.
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Objective: To compare complication rates and visual outcomes following phacoemulsification in Pugs versus dogs of other breeds.

Animals Studied: Thirty-two pure-bred Pugs (55 eyes) and 32 dogs of other breeds (56 eyes) undergoing phacoemulsification.

Procedures: Multi-institutional retrospective medical record review of perioperative factors, postoperative complications, and visual outcomes.

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This report describes the clinical presentation, diagnosis, histologic lesions, and outcome of endogenous mycotic endophthalmitis secondary to candiduria in a three-year-old female spayed Dachshund. The dog was being treated for Evans syndrome for one month prior to being diagnosed with candiduria and fibrinous uveitis OS. The left eye was enucleated due to secondary glaucoma, and the fungal urinary tract infection was treated successfully.

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Purpose: The purpose of this study was to describe breed, age, gender, and weight distribution of dogs affected with sudden acquired retinal degeneration (SARD) and to investigate whether SARD is more common in small breed dogs.

Methods: Medical records of dogs diagnosed with SARD confirmed by an electroretinogram were reviewed. Breed, age, gender, and weight were recorded when available.

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Sudden acquired retinal degeneration syndrome (SARDS) is one of the leading causes of currently incurable canine vision loss diagnosed by veterinary ophthalmologists. The disease is characterized by acute onset of blindness due to loss of photoreceptor function, extinguished electroretinogram with an initially normal appearing ocular fundus, and mydriatic pupils which are slowly responsive to bright white light, unresponsive to red, but responsive to blue light stimulation. In addition to blindness, the majority of affected dogs also show systemic abnormalities suggestive of hyperadrenocorticism, such as polyphagia with resulting obesity, polyuria, polydipsia, and a subclinical hepatopathy.

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Objective: To determine the tear production in dogs admitted to an intensive care unit (ICU).

Design: Prospective observational study from November 2010-September 2011.

Setting: Private emergency and referral hospital.

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Objective: To describe feline periocular cutaneous mast cell tumor (CMCT) clinical features, rates of local tumor recurrence and metastases, and cat survival time following surgical excision.

Animals Studied: Thirty-three cats with periocular CMCTs.

Procedures: Medical records of cats diagnosed with periocular CMCTs were reviewed; cats were included if CMCTs were surgically excised and the diagnosis confirmed by histopathology.

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Objective: To evaluate dogs with amaurosis and compare signalment, history, ophthalmic examination and neurologic abnormalities between dogs diagnosed with sudden acquired retinal degeneration syndrome (SARDS) versus neurological disease (ND). Animals Studied-140 dogs with acute vision loss and ocular abnormalities insufficient to account for visual deficits. An electroretinogram (ERG) was performed on each dog.

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Orbital disease is common in dogs and cats. Clinical signs include exophthalmos, protrusion of the third eyelid, and resistance to retropulsion of the globe. This article discusses diagnostic work-up for dogs and cats with signs suggestive of orbital disease.

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Objective: To characterize the clinical and morphologic aspects of aqueous humor misdirection syndrome (AHMS) in cats and provide a hypothesis regarding its pathogenesis on the basis of detailed analysis of affected cats.

Design: Retrospective study.

Animals: 32 cats (40 eyes).

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Objective: To evaluate the combined diode laser cycloablation procedure and adjunctive Ahmed gonioimplant use in dogs with primary glaucoma.

Design: Retrospective study.

Animals: 48 dogs, 51 eyes with primary glaucoma.

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Abnormalities in eyelid position and function can lead to chronic irritation of cornea and conjunctiva. Corneal ulceration, vascularization and pigmentation are common consequences. Loss of vision, or loss of the globe may be the end result.

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Objective: To compare sensitivity of the central and peripheral cornea of brachycephalic and Domestic Short-haired (DSH) cats.

Design: Prospective study.

Animals: Fifty DSH, thirteen Persian, and seven Himalayan cats.

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Objective: The objective of this study was to evaluate the possible relationship between the administration of parenteral and/or oral [corrected] enrofloxacin and the onset of acute retinal degeneration in cats. The animals studied included 17 cats that received systemic enrofloxacin and developed retinal degeneration soon thereafter.

Procedures: In this retrospective clinical study, cats that received parenteral and/or oral [corrected] enrofloxacin and developed acute blindness were identified.

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Objective: To describe signalment, ophthalmic abnormalities, and response to treatment in cats with glaucoma.

Design: Retrospective study.

Animals: Eighty-two cats with 93 glaucomatous eyes.

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Lens-induced uveitis.

Vet Ophthalmol

January 2000

has been described in humans and many animal species. Traumatic rupture of the lens capsule may result in vision-threatening intraocular inflammation that is poorly responsive to medical management. Phthisis bulbi, persistent uveitis or glaucoma often occurs in these eyes.

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OBJECTIVE: To determine the effect of single and multiple-dose 0.5% timolol maleate on intraocular pressure (IOP) and pupil size between 8 AM and 8 PM. Animals Nine female horses with normotensive eyes.

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Management of intraocular inflammatory disease.

Clin Tech Small Anim Pract

February 2001

The uvea of the eye is divided into the anterior uvea (iris and ciliary body) and posterior uvea (choroid). Clinical signs of anterior uveitis include conjunctival hyperemia, corneal edema, aqueous flare, miosis, and a decrease in intraocular pressure. Inflammation of the posterior uvea often involves the retina as well resulting in a chorioretinitis.

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Objective: To compare mean healing times after debridement, debridement with grid keratotomy, and superficial keratectomy in cats with nonhealing corneal ulcers.

Design: Retrospective study.

Animals: 29 cats with 36 nonhealing corneal ulcers.

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Objective: To compare in vitro and in vivo absorptive capacities of modified Schirmer tear test strips with those of original strips, and to establish reference values for use with the modified strips.

Design: Prospective study.

Animals: 100 dogs.

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The purpose of this study was to investigate the occurrence of ocular abnormalities in hyperthyroid cats. One hundred hyperthyroid cats and 30 clinically normal, geriatric cats were studied. In both groups, ophthalmic examination was performed by use of slit-lamp biomicroscopy and indirect ophthalmoscopy after application of 1% tropicamide to dilate the pupil.

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Idiopathic nonspecific inflammatory disease of the orbit (orbital pseudotumor) was diagnosed detected in a cat. The cat had progressive lagophthalmia, keratitis, and decreased motion of the right eye. Four months later, the left eye was affected in a similar manner.

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