Publications by authors named "Wiwat Iamurairat"
Population-based FMR1 carrier screening among reproductive women.
J Assist Reprod Genet
November 2024
Article Synopsis
- Fragile X syndrome (FXS) is a genetic disorder caused by an expansion of CGG repeats in the FMR1 gene, affecting neurodevelopment and passed on through female carriers who have a premutation (PM).
- A study in Thailand analyzed 1250 reproductive-age women, discovering a low prevalence of PM carriers at about 0.17% and identifying three women with gray zone alleles (0.25%).
- The findings emphasize the need for PM carrier screening among women of reproductive age to improve family planning and reproductive health, particularly to mitigate risks like fragile X-associated primary ovarian insufficiency (FXPOI).
The study was undertaken to evaluate the accuracy of sonographic morphological pattern in the detection of ovarian malignancy. A total of 123 patients with a suspicion of ovarian pathology, who were scheduled for elective surgery at the Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University were included in the study. All patients underwent sonographic examination prior to surgery by the same physician.
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