Publications by authors named "Witawas Handee"

In a modern society that is increasingly older and "heavier," it is understandable that the majority favors a slimmer body that helps to sail smoothly into the dusk of life. Given the association between obesity and many metabolic and cardiovascular disorders, there are stern criticisms over such a thought of "good fat". Ironically, a phenomenon called "obesity paradox", that is, the overweight population purportedly enjoys the lowest all-cause mortality, and baffles open-minded clinicians and scientists.

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Intracellular triacylglycerol (TAG) is a ubiquitous energy storage lipid also involved in lipid homeostasis and signaling. Comparatively, little is known about TAG's role in other cellular functions. Here we show a pro-longevity function of TAG in the budding yeast Saccharomyces cerevisiae.

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Article Synopsis
  • Unicellular marine algae, particularly the genus Nannochloropsis, are potential sources for sustainable biofuels, but there is a lack of optimal species and genetic resources for their engineering.
  • Nannochloropsis oceanica has been successfully genetically modified, revealing significant information about its genome (28.7 Mb) and a total of 11,973 genes, including over 100 related to lipid metabolism.
  • The study also compares N. oceanica's genes to those of N. gaditana, identifying unique genes and provides protocols for transforming N. oceanica, aiding future genetic research.
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