Publications by authors named "Wissem Aidi Wannes"

Plants constitute a source of natural phytochemical components which are widely known for their potential biological activities. This work concerned a study of the antioxidant, anticancer and anti-inflammatory activities of squirting cucumber (Ecballium elaterium L.) parts (flowers, fruits, leaves and stems) using different solvent extracts (cyclohexane, dichloromethane, ethyl acetate, methanol and water).

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  • This study explores the use of cyclopentyl methyl ether (CPME) as a more efficient and environmentally friendly alternative to hexane for extracting fenugreek seed oil.
  • In simulations and experiments, CPME outperformed hexane, yielding 7.23% oil compared to hexane's 4.25% and preserving more beneficial fatty acids and bioactive compounds.
  • CPME also demonstrates better oxidative stability and lower volatile organic compound emissions, making it a sustainable option for oil extraction while offering improved antioxidant and antibacterial properties.
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This study endeavoured to capitalize on prickly pear by-products for the optimization of molasses formulation, targeting elevated antioxidant capacities and superior sugar contents. Through robust statistical modelling, the optimal cooking parameters-temperature (70-80 °C) and duration (60-90 min)-were determined, guided by responses of antioxidant activity and Brix value. A D-Optimal mixture design further delineated the ideal proportions of molasses components (pulp, peel, and seeds).

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  • - The study analyzed extracts of cypress from three regions in Tunisia (Bizerte, Ben Arous, and Nabeul) for their antioxidant and antibacterial properties, as well as their phenolic content.
  • - Bizerte's methanol extract showed the highest phenolic content (315.75 mg GAE/g DW), with cupressuflavone being the main compound (68%).
  • - The ethanol extract from Nabeul was particularly effective against Gram-positive bacteria, showing a significant inhibition zone of 40 mm, highlighting cypress as a promising source for natural antioxidants and antibacterial agents.
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The present study aimed to investigate the qualitative and quantitative performance of five green solvents, namely 2-methyltetrahydrofuran (MeTHF), cyclopentyl methyl ether (CPME), -cymene, -limonene and ethanol to substitute -hexane, for sesame seed oil extraction. In fact, both CPME and MeTHF gave higher crude yields than -hexane (58.82, 54.

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The aerial parts of cypress ( L.) of three collect regions (Bizerte, Ben-Arous and Nabeul) were reported for their essential oil (EO) compositions, antioxidant, antimicrobial and insecticidal activities. Results showed that the higher EO yields were observed in Bizerte and Ben Arous (0.

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This study examined the antioxidant, anticancer and antiviral properties of the methanolic extracts from bigarade ( L.) leaves at two development stages. Ferulic acid, naringin and naringenin were the principal phenolic components of young and old leaves.

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The organic solvent extracts (hexane, chloroform, acetone, methanol and water) of coriander fruits were reported for their antioxidant and repellent activities. The methanol and acetone extracts revealed the highest antiradical activity as compared to the other solvent extracts. HPLC analysis revealed that phenolic acids were the major compounds in chloroform and acetone extracts, whereas flavonoids in methanol and water extracts.

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The methanolic extracts of cypress ( L.) collected at three phenological stages were evaluated for their cytotoxicity on Vero cells by MTT test as well as on (HSV-2) and coxsackie (CVB-3) viruses by plaque reduction assay. The methanolic extract exhibited the highest cytotoxicity against HSV-2 (IC = 20.

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is used as a medicinal herb in many countries. In this study, cyclohexane, dichloromethane, ethyl acetate, methanol and water were used as solvents in the extraction of fruits. The contents of total phenolics, total flavonoids, total tannins and condensed tannins as well as the biological activities of these extracts were investigated using various and assays.

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  • The study investigated the antifungal effects of laurel, myrtle, and peppermint essential oils on the mycelial growth of Alternaria alternata and on Citrus leaf disease.
  • Myrtle oil contained α-pinene and 1,8-cineole, while peppermint oil was rich in menthol and menthone, with laurel oil primarily composed of 1,8-cineole.
  • The essential oils effectively inhibited fungal growth at a concentration of 3 mg/mL, with a notable synergistic effect observed when peppermint and laurel oils were combined, significantly reducing mycelial growth on infected leaves at concentrations above 1.5 mg/mL.
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This research aimed to study the chemical composition of   methanolic extract and its biological activities as an antioxidant, and its antibacterial, antifungal and anti-inflammatory activities based on four bioclimatic collection stages. The contents of total phenols, total flavonoids and total tannins were determined. Nine phenolic compounds were identified by LC-DAD-ESI-MS/MS.

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The aim of this study was to optimize the mechanical and texture properties of edible film improving its antibacterial property after adding rosemary essential oil (REO) using a Doehlert matrix. Films with the highest mechanical properties were acquired using a polymer composition of 65.2% glycerol, 24.

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This study was designed to examine the effect of provenance on the phytochemical and antioxidant properties of essential oil and methanolic extract from Tunisian and French fennel seeds (FFS). Analysis of the essential oil showed that although the same main compounds were found in Tunisian and FFS cultivars, some differences were present in their proportions allowing to classify them in two chemotypes. The first class was composed by trans-anethole (63.

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Triterpenoids, tocopherols, and phytosterols presented in unsaponifiable fraction of grape seed oil have several beneficial effects comprising antioxidant, anti-inflammatory, and antitumor capacities. In this study, the unsaponifiable fraction of three Tunisian grape seed varieties (Vitis vinifera L.), namely Merlot, Carignan, and Syrah, was investigated.

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This study was conducted to investigate potentially protective and curative effects of root (turmeric) powder on CCl-induced hepatotoxicity in rats. Turmeric was administered before (preventive effect) or after (curative effect) treatment with CCl. Total phenolic and flavonoid levels were 26.

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Cancer is a major public health problem in the world. The use of the medicinal plants in cancer prevention and management is frequent in Africa, especially in Tunisia, and it is transmitted from generation to generation within cultures. Many previous studies showed that a wide range of Tunisian medicinal plants exerted cytotoxic and anticancer activity.

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This study aimed to characterize the chemical composition and antioxidant activity of the oil and the methanolic extract of Myrtus communis var. baetica seed. The oil yield of myrtle seed was 8.

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The present investigation focuses on the methanolic extract obtained from Geranium robertianum L. (Geraniaceae) (Herb Robert), a herbal plant used in traditional medicine for the treatment of human and animal diseases. The antioxidant capacities of the extract were evaluated using 1,1-diphenyl-2-picrylhydrazyl radical, β-carotene/linoleic acid and reducing power and metal chelating activity assays.

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Background: Juices from four Citrus species of Tunisia were investigated mainly for quality parameters and antioxidant capacity.

Results: Citrus reticulata (mandarin) juice had the highest content of total flavonoids (85.33 mg CE L(-1)).

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Cuminum cyminum L. roots, stems and leaves, and flowers were investigated for their essential oils, total phenolics, flavonoids, and tannins contents, individual phenolic compounds, and antioxidant activities. The essential oil was investigated by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS), whereas identification and quantification of individual target polyphenolic compounds was performed by reversed-phase high-performance liquid chromatography (RP-HPLC).

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This study was designed to examine the chemical composition and antioxidant activity of the essential oils and methanol extracts of Myrtus communis var. italica L. leaf, stem and flower.

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Two Myrtus communis varieties (var. italica and baetica) were studied in order to investigate their essential oil yield and composition. Essential oil yield varied in leaves, fruits and stems.

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Borago officinalis rosette leaves were sampled in the region of Amdoun (Tunisia) during different stages of their development. Essential oil contents varied from 0.01% to 0.

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