Outcomes of local excision for early rectal cancer: a 6-year experience from the largest university hospital in Thailand.

Background: This study aimed to determine clinical outcomes of local excision for early rectal cancer from a University Hospital in Thailand.

Materials And Methods: We performed a retrospective review of 22 consecutive patients undergoing local excision for early rectal cancer (clinical and radiological T1/T2) from 2005-2010 at the Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok. Data were collected from patients' medical records, including demographic and clinical characteristics, pathological report and surgical outcomes.

Successful treatment of esophageal metastasis from hepatocellular carcinoma using the da Vinci robotic surgical system.

A 59-year-old man with metastatic an esophageal tumor from hepatocellular carcinoma (HCC) presented with progressive dysphagia. He had undergone liver transplantation for HCC three and a half years prevously. At presentation, his radiological and endoscopic examinations suggested a submucosal tumor in the lower esophagus, causing a luminal stricture.

The surgical outcome of preoperative chemoradiation therapy for ultra low rectal cancer.

Objective: To evaluate the surgical outcome of preoperative long-course chemoradiation therapy (PCRT) in patients with ultra low rectal cancer.

Material And Method: Medical records of patients with rectal adenocarcinoma located within the length of 5 cm from the anal verge, who underwent elective oncological resection between 2003 and 2006 at Siriraj Hospital, were reviewed. PCRT was performed in some patients based on tumor characteristics and surgeon's decision.

Comparison between midline and right transverse incision in right hemicolectomy for right-sided colon cancer: a retrospective study.

Background: The advantage of a transverse incision over a midline incision for open right hemicolectomy remains controversial.

Objective: To compare the short-term surgical outcomes of right hemicolectomy through midline incision (RHML) and right hemicolectomy through right transverse incision (RHTR) for right-sided colon cancer.

Material And Method: This retrospective study included 74 patients with right-sided colon cancer who underwent elective right hemicolectomies through midline or right transverse incision between February 2004 and June 2006 at the Department of Surgery, Faculty of Medicine Siriraj Hospital.

Preoperative chemoradiation for locally advanced rectal cancer with capecitabine 2,000 mg/m2/day.

Objective: Evaluate the efficacy and the tolerability of preoperative chemoradiation with high dose Capecitabine.

Material And Method: Fifteen patients with locally advanced resectable rectal cancer were treated with Capecitabine 2,000 mg/m2/day, orally 7 days/week concurrent with whole pelvic irradiation 45 Gy in 25 fractions/5 weeks. Patients underwent surgery in the following 4-6 weeks.

Outcomes of sphincter-saving operation for rectal cancer without protective stoma and pelvic drain, and risk factors for anastomotic leakage.

Background/aims: To evaluate the outcomes of sphincter-saving operation for rectal cancer without protective stoma and pelvic drain and to determine factors influencing anastomotic leakage.

Methods: We investigated 170 patients undergoing elective sphincter-saving operation without protective stoma and pelvic drain during 2003-2006 in a single institution. Early postoperative outcomes were evaluated.

Pre-operative hypoalbuminemia is a major risk factor for postoperative complications following rectal cancer surgery.

Aim: To determine the relationship between pre-operative hypoalbuminemia and the development of complications following rectal cancer surgery, as well as postoperative bowel function and hospital stay.

Methods: The medical records of 244 patients undergoing elective oncological resection for rectal adenocarcinoma at Siriraj Hospital during 2003 and 2006 were reviewed. The patients had pre-operative serum albumin assessment.

Hypoalbuminemia is a predictor of delayed postoperative bowel function and poor surgical outcomes in right-sided colon cancer patients.

Purpose: To determine the relationship between preoperative serum albumin and postoperative bowel function as well as surgical outcomes in right-sided colon cancer patients.

Methods: This retrospective study in a university hospital included 84 patients who underwent elective right hemicolectomy for adenocarcinoma of the right-sided colon between January 2004 and December 2005. The patients had a preoperative serum albumin assessment.

Surgical outcomes of Lichtenstein tension-free hernioplasty for acutely incarcerated inguinal hernia.

Purpose: The purpose of our study was to evaluate the short-term and long-term outcomes of emergency Lichtenstein tension-free hernioplasty for acutely incarcerated inguinal hernia.

Methods: We conducted a retrospective study of patients who underwent emergency Lichtenstein hernioplasty for acutely incarcerated inguinal hernia between September 2002 and January 2006 in a major city hospital in Thailand. We analyzed the early postoperative complications and surgical outcomes.

Preoperative capecitabine with pelvic radiotherapy for locally advanced rectal cancer (phase I trial).

Objective: Phase I multicenter study defined the maximal tolerated dose (MTD), dose-limiting toxicity (DLT) and safety profile of capecitabine in combination with preoperative radiation for patients with locally advanced rectal cancer (LARC).

Material And Method: Patients were treated with oral capecitabine (700, 800, 900, 1000, 1100 and 1200 mg/m2 twice daily continuously) plus preoperative whole pelvic irradiation (45-46 Gy in 23-25 fractions over 5-6 weeks). Surgery was performed at the median of 42 days after chemoradiation treatment.

Surgical management of adult choledochal cysts.

Objectives: Results of the surgical management of 17 choledochal cysts in adults at the Department of Surgery, Siriraj Hospital, Mahidol University, are presented

Material And Method: All the patients who underwent diagnosis and were surgically managed during the period between October 1990 and January 1999 were analyzed retrospectively. Cysts were classified anatomically according to the descriptions of Todani et al. The authors assessed the clinical features, operative procedure and outcome of the patients.

A phase II study to evaluate WF10 in patients with late hemorrhagic radiation cystitis and proctitis.

Objective: To evaluate efficacy and safety of WF10 (TCDO iv solution) therapy in patients with late hemorrhagic radiation cystitis and proctitis in a long-term follow up.

Material And Methods: From February 1999 to July 2001, 30 symptomatic patients with endoscopically confirmed grade 2 and 3 late hemorrhagic cystitis (n = 16) and proctitis (n = 14) were treated with WF10. The dose was 0.

Whipple's operation without an operative mortality in 37 consecutive patients: Thai surgeons' experiences.

Objective: Pancreaticoduodenectomy (Whipple's operation) represents a considerable surgical challenge. The operative mortality rate after Whipple's operation is still less than 5%. Recent studies show pancreaticojejunostomy (PJ) anastomosis is the "Achilles heel" of the procedure.