Influence of the 6-month anemia therapy with erythropoietin on renal function and some hemodynamic parameters in predialysis patients.

Objectives: The aim of this study was to evaluate the influence of a 6-month anemia therapy with recombinant human erythropoietin (rHuEpo) on glomerular filtration rate (GFR) and renal blood flow related to hemoglobin (Hb) concentration, changes in heart function and total peripheral resistance in patients with chronic kidney disease (CKD) treated conservatively.

Patients And Methods: We evaluated 13 patients (9 women and 4 men) aged 64.8 +/- 8.