[The problem of increased vitamin D level in a group of patients hospitalized in a geriatrics clinic].

Background: Taking into account the multi-directional beneficial effects of vitamin D and its widespread deficiency, regular supplementation is recommended. However, more and more attention is being paid to the risk of overdose with supplemented vitamin D and the associated serious health consequences.

Material And Methods: The concentration of 25-hydroxyvitamin D (25(OH)D) is a routine test recommended upon admission to the Geriatrics Clinic of Wroclaw Medical University.

[Problem of depression in patients with bronchial asthma].

Introduction: The aim of this study was to evaluate the frequency of various degrees of depressive disorders in patients diagnosed with bronchial asthma of different degrees of severity.

Material And Methods: The study involved 120 patients - 80 with bronchial asthma from mild to severe and various prevalence of the disease hospitalized in The Department of Internal Medicine, Geriatrics and Allergology, Medical University in Wroclaw, and 40 patients without chronic lung's disease as the control group. The methods included a structural interview, body examination and spirometry.

Exercise-induced bronchospasm among athletes in Lower Silesia Province.

A few studies have reported data on the prevalence of exercise-induced bronchospasm in high school and university athletes. Recently published data suggest that exercise-induced bronchospasm may affect up to 39% of American university athletes. To date, no data describing this pathology in athletes from Central Europe have been published.

[Efficacy and safety of specific immunotherapy of upper airways allergic diseases caused by allergy to mites].

Aim Of The Study: The aim of this study was to evaluate the efficacy and safety of 3 years oral specific immunotherapy in patients with perannial allergic rhinitis and bronchial asthma caused by allergy to mites.

Material And Methods: Fifteen patients with allergic perannial rhinitis entered the study. Ten of them suffered also from bronchial asthma.

[Modern views on the role of neutrophil in the pathogenesis of bronchial asthma].

In this study the authors presented modern views concerning neutrophil participation in allergic inflammation and some literature data suggesting the possibility of neutrophil specific activation by extrinsic allergens.

[Studies of the specificity of immediate allergic reactions to ampicillin].

Ampicillin belongs to the drugs causing most frequently IgE-dependent allergic reactions, but the current specificity of these reactions is poorly known. Some experimental data suggest that the side chain of ampicillin may induce synthesis of drug-specific IgE antibodies. In our study we have decided to explain the specificity of ampicillin-induced allergic reactions type I appearing in patients after drug administration.

[Neutrophil myeloperoxidase release by selected extrinsic allergens].

In this study the authors investigated myeloperoxidase release from peripheral blood neutrophils isolated from patients with allergic respiratory tract diseases and from healthy subjects, induced by selected extrinsic allergens. We have observed the same degree of myeloperoxidase release from neutrophils isolated from both patients with allergic respiratory tract diseases and healthy subjects after stimulation by selected allergens (Dermatophagoides pteronyssinus, Grass mix). Moreover, control allergens (to which allergic persons were not sensitized) also caused myeloperoxidase release from neutrophils isolated from patients with allergic diseases of the airways.