A COMPARISON OF THE EFFECTS OF PYRIDOXINE AND PANTOTHENIC ACID DEFICIENCIES ON THE NERVOUS TISSUES OF SWINE.

1. When pigs were fed diets deficient in pyridoxine or pantothenic acid, ataxia developed and lesions were found in the sensory neuron. 2.

SENSORY NEURON DEGENERATION IN VITAMIN DEFICIENCY : DEGENERATION OF THE POSTERIOR COLUMNS OF THE SPINAL CORD, PERIPHERAL NERVES, AND DORSAL ROOT GANGLION CELLS IN YOUNG PIGS FED A DIET CONTAINING THIAMIN (B(1)) AND RIBOFLAVIN BUT OTHERWISE DEFICIENT IN VITAMIN B COMPLEX.

Young pigs were given an artificial diet presumably adequate in all respects. As they developed, the quantity of yeast was gradually reduced while thiamin (vitamin B(1)) and riboflavin were given in its place. The rate of growth decreased, the general condition of the animals became impaired, and marked ataxia without motor weakness developed.