EEG-based brain age prediction in infants-toddlers: Implications for early detection of neurodevelopmental disorders.

The infant brain undergoes rapid developmental changes in the first three years of life. Understanding these changes through the prediction of chronological age using neuroimaging can provide insights into typical and atypical brain development. We utilized 938 resting-state EEG recordings from 457 typically developing infants, 2 to 38 months old, to develop age prediction models.

Prediction of chronological age from resting-state EEG power in the first three years of life.

The infant brain undergoes rapid and significant developmental changes in the first three years of life. Understanding these changes through the prediction of chronological age using neuroimaging data can provide insights into typical and atypical brain development. We utilized longitudinal resting-state EEG data from 457 typically developing infants, comprising 938 recordings, to develop age prediction models.

Bilateral Corticomotor Reorganization and Symptom Development in Response to Acute Unilateral Hamstring Pain: A Randomized, Controlled Study.

Accumulating evidence demonstrates that pain induces adaptations in the corticomotor representations of affected muscles. However, previous work has primarily investigated the upper limb, with few studies examining corticomotor reorganization in response to lower limb pain. This is important to consider, given the significant functional, anatomical, and neurophysiological differences between upper and lower limb musculature.

Neural response to repeated auditory stimuli and its association with early language ability in male children with Fragile X syndrome.

Background: Fragile X syndrome (FXS) is the most prevalent form of inherited intellectual disability and is commonly associated with autism. Previous studies have linked the structural and functional alterations in FXS with impaired sensory processing and sensory hypersensitivity, which may hinder the early development of cognitive functions such as language comprehension. In this study, we compared the P1 response of the auditory evoked potential and its habituation to repeated auditory stimuli in male children (2-7 years old) with and without FXS, and examined their association with clinical measures in these two groups.

Decoding auditory attention from EEG using a convolutional neural network.

Brain-computer interface (BCI) systems allow users to communicate directly with a device using their brain. BCI devices leveraging electroencephalography (EEG) signals as a means of communication typically use manual feature engineering on the data to perform decoding. This approach is time intensive, requires substantial domain knowledge, and does not translate well, even to similar tasks.

How do training experience and geographical origin of a runner affect running biomechanics?

Background: Several studies compared African runners with runners from other places with difference ethnicities to identify biomechanical factors that may contribute to their extraordinary running performance. However, most studies only assessed runners at the elite level. Whether the performance difference was a result of nature or nurture remains unclear.

Decoding auditory attention from single-trial EEG for a high-efficiency brain-computer interface.

Brain-computer interface (BCI) systems enable humans to communicate with a machine in a non-verbal and covert way. Many past BCI designs used visual stimuli, due to the robustness of neural signatures evoked by visual input. However, these BCI systems can only be used when visual attention is available.

Neurophysiological Correlates of Gait Retraining With Real-Time Visual and Auditory Feedback.

Most people acquire motor skills through feedback-based training. How the human brain processes sensory feedbacks during training, especially in a gait training, remain largely unclear. The purpose of this paper is to explore how humans adopt a new gait pattern to reduce impacts during walking-with the aid of visual and audio feedbacks.

Transfer Learning Effects of Biofeedback Running Retraining in Untrained Conditions.

Purpose: Running gait retraining via peak tibial shock biofeedback has been previously shown to reduce impact loading and mitigate running-related symptoms. In previous research, peak tibial shock is typically measured and trained for one limb at a single constant training speed during all training sessions. The goal of this study was to determine how runners transfer learning in the trained limb to the untrained limb at different unconstrained speeds.

Shoe-mounted accelerometers should be used with caution in gait retraining.

Real-time biofeedback gait retraining has been reported to be an effective intervention to lower the impact loading during gait. While many of the previous gait retraining studies have utilized a laboratory-based setup, some studies used accelerometers affixed at the distal tibia to allow training outside the laboratory environment. However, many commercial sensors for gait modification are shoe-mounted.

Can runners maintain a newly learned gait pattern outside a laboratory environment following gait retraining?

Background: Previous peak tibial shock gait retraining programs, which were usually conducted on a treadmill, were reported to be effective on impact loading reduction in runners. However, whether the trained runners can translate the training effect at different running modes (treadmill/overground), or running slopes (uphill/downhill), remains unknown.

Research Question: Is the training effect from a treadmill-based gait retraining translatable to unconstrained running conditions, including overground and uphill/downhill running?

Methods: The peak tibial shock was measured during treadmill/overground running, as well as level/uphill/downhill running before and after a course of treadmill-based gait retraining.

Impact Loading During Distracted Running Before and After Auditory Gait Retraining.

Visual feedback gait retraining has been reported to successfully reduce impact loading in runners, even when the runners were distracted. However, auditory feedback is more feasible in real life application. Hence, this study compared the peak positive acceleration (PPA), vertical average (VALR) and instantaneous (VILR) loading rate during distracted running before and after a course of auditory feedback gait retraining in 16 runners.

Type effect of inhibitory KT tape on measured vs. perceived maximal grip strength.

This study examined the effects of KT tape (KT) applied in an inhibitory manner on muscle activity, measured maximal grip strength, and perceived maximal grip strength in regular KT-users and non-users. This study was a single-blinded crossover study with sixty participants including 27 kT-users and 33 non-users. Participants underwent maximal grip strength tests with and without inhibitory KT applied across the wrist extensors.

Placebo effect of facilitatory Kinesio tape on muscle activity and muscle strength.

Purpose: Kinesio tape (KT) is claimed to be able to facilitate muscle activation and promote muscle strength. Previous studies have proposed that placebo effect could be a major attributing factor. This study sought to compare the effects of facilitatory KT on muscle activity and performance between regular KT-users and non-users.

Control of impact loading during distracted running before and after gait retraining in runners.

Gait retraining using visual biofeedback has been reported to reduce impact loading in runners. However, most of the previous studies did not adequately examine the level of motor learning after training, as the modified gait pattern was not tested in a dual-task condition. Hence, this study sought to compare the landing peak positive acceleration (PPA) and vertical loading rates during distracted running before and after gait retraining.

Gait Retraining for the Reduction of Injury Occurrence in Novice Distance Runners: 1-Year Follow-up of a Randomized Controlled Trial.

Background: The increasing popularity of distance running has been accompanied by an increase in running-related injuries, such that up to 85% of novice runners incur an injury in a given year. Previous studies have used a gait retraining program to successfully lower impact loading, which has been associated with many running ailments. However, softer footfalls may not necessarily prevent running injury.

Effects of Kinesio tape in individuals with lateral epicondylitis: A deceptive crossover trial.

Objectives: To determine the true and immediate effect of applying Kinesio tape (KT) on the pain intensity, pain-free grip strength, maximal grip strength, and electromyographic activity with facilitatory KT, inhibitory KT, sham KT, and untaped condition in patients with lateral epicondylitis (LE) who were ignorant about KT.

Design: Deceptive crossover trial.

Participants: Thirty-three patients with unilateral chronic LE who were ignorant about KT, 30 of them were successfully deceived in this study.

Measurement agreement between a newly developed sensing insole and traditional laboratory-based method for footstrike pattern detection in runners.

This study introduced a novel but simple method to continuously measure footstrike patterns in runners using inexpensive force sensors. Two force sensing resistors were firmly affixed at the heel and second toe of both insoles to collect the time signal of foot contact. A total of 109 healthy young adults (42 males and 67 females) were recruited in this study.

Immediate and short-term biomechanical adaptation of habitual barefoot runners who start shod running.

This study investigated the immediate and short-term effects of minimalist shoes (MS) and traditional running shoes (TRS) on vertical loading rates, foot strike pattern and lower limb kinematics in a group of habitual barefoot runners. Twelve habitual barefoot runners were randomly given a pair of MS or TRS and were asked to run with the prescribed shoes for 1 month. Outcome variables were obtained before, immediate after and 1 month after shoe prescription.

A new footwear technology to promote non-heelstrike landing and enhance running performance: Fact or fad?

This study sought to compare the kinetics and kinematics data in a group of habitual shod runners when running in traditional running shoes and newly designed minimalist shoes with lug platform. This novel footwear design claims to simulate barefoot running and reduce energy loss during impact. We compared footstrike angle (FSA), vertical average (VALR) and instantaneous (VILR) loading rates, energy loss and initial vertical stiffness between two shoe conditions.

Comparison of the correlations between impact loading rates and peak accelerations measured at two different body sites: Intra- and inter-subject analysis.

Background: High average (VALR) and instantaneous vertical loading rates (VILR) during impact have been associated with many running-related injuries. Peak acceleration (PA), measured with an accelerometer, has provided an alternative method to estimate impact loading during outdoor running. This study sought to compare both intra- and inter-subject correlations between vertical loading rates and PA measured at two body sites during running.

Lower limb reaction force asymmetry in rowers with and without a history of back injury.

Back injury is common in rowers. Asymmetrical lower limb reaction force on the foot stretchers during rowing may compromise trunk biomechanics and lead to back injury. However, such a mechanism remains putative.