Publications by authors named "Winfried Geis"
Article Synopsis
- Genetically-modified therapies like CAR-T are really effective at fighting tough blood cancers but making them is complicated.
- Researchers used a special method called quality-by-design (QbD) to improve how CAR-T cells are made, focusing on things like how many times the cells are turned on and how crowded they are in their growing environment.
- They found that doing a single activation step and growing the cells for a shorter time helped create way more healthy CAR-T cells, which worked just as well when tested on a bigger scale.
