Publications by authors named "Wince W"

Article Synopsis
  • The SCMR Registry is a comprehensive database that collects clinical data from cardiovascular magnetic resonance (CMR) exams, supporting research on treatment outcomes and advancing machine learning in cardiovascular health.
  • As of now, it contains data from over 154,000 CMR scans across 20 sites in the U.S., including a vast 100 terabytes of imaging data, revealing demographics such as an average patient age of 58 and a notable 8% mortality rate in the studied cohort.
  • Significant findings indicate a higher mortality risk associated with certain indicators, such as a left ventricular ejection fraction below 35% and specific wall motion abnormalities, showcasing the registry’s potential to enhance clinical insight and improve patient outcomes.
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Objective: The objective of this study was to correlate early recurrence of atrial fibrillation (AF) after ablation with noninvasive imaging using cardiac computed tomography (CT).

Methods: CT image data of 260 patients who had undergone wide area circumferential ablation (WACA) between October 2005 and August 2010 as well as from 30 subjects in sinus rhythm without a history of AF (control group) were retrospectively analyzed. To evaluate early outcome of AF ablation, all AF patients underwent follow-up with a 30-day event monitor 3 to 4 months after ablation.

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Rationale: After acute myocardial infarction (MI), delineating the area-at-risk (AAR) is crucial for measuring how much, if any, ischemic myocardium has been salvaged. T2-weighted MRI is promoted as an excellent method to delineate the AAR. However, the evidence supporting the validity of this method to measure the AAR is indirect, and it has never been validated with direct anatomic measurements.

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Background: Thoracic aortic aneurysms (TAAs) develop secondary to abnormal aortic extracellular matrix remodeling, resulting in a weakened and dilated aortic wall that progressed to rupture if left unattended. Currently, no diagnostic/prognostic tests are available for the detection of TAA disease. This is largely driven by the lack of a large animal model, which would permit longitudinal/mechanistic studies.

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