Publications by authors named "Win N"

The guide extension-facilitated ostial stenting (GEST) technique uses a guide extension catheter (GEC) to improve stent delivery during primary coronary angioplasty (PCI). GECs are used for stent delivery into the coronary arteries of patients with difficult anatomy due to tortuosity, calcification, or chronic total occlusion (CTO) vessels. Stent and balloon placement has become challenging in patients with increasing lesion complexity due to tortuosity, vessel morphology, length of the lesion, and respiratory movements.

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  • More than a third of peripheral intravenous cannulas (PIVCs) inserted in hospitals remain unused, highlighting issues with documentation and potential complications.
  • A quality improvement project involved conducting an initial audit, implementing changes, and a follow-up audit to assess adherence to a PIVC care bundle.
  • The project aimed for a target adherence score of 90-100% on PIVC documentation and care; results showed a comparison between the first and second cycles, with improved scores indicating successful implementation.
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Breast cancer stands as a formidable danger to the health of women worldwide, underscoring the critical need for effective screening methods. Multispectral transmission imaging offers a promising avenue due to its non-invasive potential for early screening. Some researchers already suggested registration to solve the problem of jitters due to respiration and movement and frame accumulation technology to solve the low grayscale problem.

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Early detection of Alzheimer's disease (AD) is crucial to maximize clinical outcomes. Most disease progression analyses include people with diagnoses of cognitive impairment, limiting understanding of AD risk among those with normal cognition. The objective was to establish AD progression models through a deep learning approach to analyze heterogeneous, multi-modal datasets, including clustering analyses of population subsets.

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Genetic transformation is a critical tool for gene manipulation and functional analyses in plants, enabling the exploration of key phenotypes and agronomic traits at the genetic level. While dicotyledonous plants offer various tissues for in vitro culture and transformation, monocotyledonous plants, such as rice, have limited options. This study presents an efficient method for genetically transforming rice ( L.

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Background: The Impact of Vision Impairment (IVI) questionnaire is used to assess vision-related quality of life (VRQOL) among patients with visual impairment. This study aims to evaluate the factor structure of the IVI in the context of Thai culture to assess psychometric properties.

Methods: This cross-sectional study was conducted between February and July 2022.

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  • The study investigates how teleneurology affects healthcare utilization (HCU) for patients with multiple sclerosis (MS) and clinically isolated syndrome (CIS) in the Cleveland/Akron area from July 2020 to July 2022.
  • Findings show that patients using teleneurology had more visits but required fewer laboratory and MRI orders, indicating efficient use of healthcare resources.
  • Despite the increased visit volumes, there was no rise in emergency care utilization, although higher emergency visits were noted among Black and Medicaid patients, highlighting a need for further research.
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  • The study examines the genetic characteristics of influenza A(H1N1)pdm09 strains found in Myanmar between 2015 and 2019, utilizing advanced sequencing techniques to analyze 60 virus isolates.
  • It identifies distinct clades for each year’s virus, noting that strains from these years were genetically different from WHO-recommended Southern Hemisphere vaccine strains.
  • The researchers also discovered a virus with reassortment and three strains with the H275Y mutation, indicating reduced effectiveness against antiviral treatments, highlighting the need for ongoing monitoring of flu virus genetics for vaccine development.
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Background: During the COVID-19 pandemic, use of telemedicine (TM) increased dramatically, but it is unclear how use varies by characteristics of people with Alzheimer's disease (AD), multiple sclerosis (MS), or Parkinson's disease (PD).

Methods: This cross-sectional study used US PharMetrics Plus commercial claims data from January 1, 2019, to December 31, 2021. TM use (≥1 Current Procedural Terminology code) was assessed in each study year (2019, 2020, and 2021) among people with ≥1 inpatient or ≥2 outpatient diagnosis codes ≥30 days apart for AD, MS, or PD.

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Background: Many youths suffer from depressive symptoms globally, especially youth migrant workers who are more vulnerable to depressive symptoms than non-migrant youths. Given the extensive literature reviewed, little is known about the impact of stressors on depressive symptoms among young migrant populations. Therefore, this study aimed to investigate the impact of stressors on depressive symptoms among young Myanmar migrants in Thailand.

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Objective: Perseverative cognitive processes, such as rumination, may indirectly influence effects of personality traits on cannabis use and related problems. Understanding relations among personality, rumination, and cannabis use motives may lead to better understanding of problematic cannabis use. The present study examined personality traits' influence on negative cannabis-related consequences via rumination and cannabis use coping motives.

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  • Enterovirus D68 (EV-D68) is a reemerging virus linked to serious respiratory infections and paralysis, mainly affecting children, with outbreaks reported in various regions since 2014 but not in Southeast Asia until now.
  • A study in Myanmar collected nasopharyngeal swabs from children aged 1 month to 12 years admitted with acute lower respiratory infections, using a specialized PCR method to detect EV-D68.
  • The study found EV-D68 in 42 out of 570 samples (7.4%), with all strains identified as clade B3, marking the first detection of this virus in children in Yangon and highlighting the need for ongoing surveillance in Southeast Asia.
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The gap between expectations and reality could lead to low job satisfaction. Although much literature has been described on job satisfaction among different categories of people, more research is needed to acknowledge the judgment of job satisfaction among some of the Myanmar working population. The study aims to find out the satisfaction level of a job and the factors related to it.

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Anthocyanin accumulation is responsible for the coloration of apple fruit, and their accumulation depends on the expression of anthocyanin biosynthesis-related genes. Light is an environmental stimulus that induces fruit color by regulating genes involved in the anthocyanin biosynthesis pathway. In this study, the roles of light and genetic factors on fruit coloration and anthocyanin accumulation in apple fruit were investigated.

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Background: Athletes have changes that can mimic pathological cardiomyopathy.

Methods: Echocardiographic study of 50 male, female athletes (MA, FA) and non-athletes (MNA, FNA) age 18 to 30 years. These athletes participate in sports with predominantly endurance component.

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  • Parechovirus-A (PeV-A) is an emerging virus affecting children, with symptoms varying by genotype, but research has mostly focused on developed countries, leaving a knowledge gap in places like Myanmar.* -
  • This study analyzed nasopharyngeal samples from hospitalized children aged 1 month to 12 years at Yankin Children Hospital over two years to detect and genotype PeV-A.* -
  • Out of 570 samples, 11 were positive for PeV-A, revealing four different genotypes in Myanmar, with a median patient age of 10 months, indicating the need for further research on its clinical effects.*
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Gestational diabetes mellitus (GDM) contributes to maternal and neonatal morbidity. As data from marginalized populations remains scarce, this study compares risk-factor-based to universal GDM screening in a low resource setting. This is a secondary analysis of data from a prospective preterm birth cohort.

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Background: Disability is globally recognized as a key cause of depression. Likewise, the COVID-19 pandemic has significantly increased the vulnerability of patients with low vision to health and health-related issues, especially mental health. This study aimed to examine the association between the impact of COVID-19 and depressive symptoms in patients with low vision and blindness.

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An influenza circulation was observed in Myanmar between October and November in 2021. Patients with symptoms of influenza-like illness were screened using rapid diagnostic test (RDT) kits, and 147/414 (35.5%) upper respiratory tract specimens presented positive results.

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This study aimed to analyze the genetic and evolutionary characteristics of the influenza A/H3N2 viruses circulating in Myanmar from 2015 to 2019. Whole genomes from 79 virus isolates were amplified using real-time polymerase chain reaction and successfully sequenced using the Illumina iSeq100 platforms. Eight individual phylogenetic trees were retrieved for each segment along with those of the World Health Organization (WHO)-recommended Southern Hemisphere vaccine strains for the respective years.

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Bemisia tabaci is a species complex consisting of various genetically different cryptic species worldwide. To understand the genetic characteristics and geographic distribution of cryptic species of B. tabaci in Asia, we conducted an extensive collection of B.

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Plant viruses are responsible for the most devastating and commercially significant plant diseases, especially in tropical and subtropical regions. The genus is the largest one in the family with a single-stranded DNA genome, either monopartite or bipartite. Begomoviruses are transmitted by insect vectors, such as .

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β-Thalassemia (β-thal) is highly prevalent in Myanmar, but limited data are available on the molecular basis and the clinical manifestations in Myanmar patients. In this study, we investigated the clinical features and β-globin gene abnormalities in 15 homozygous β-thal and 60 Hb E (: c.79G>A)/β-thal pediatric patients who attended Yangon Children Hospital, the biggest thalassemia day care unit center in Myanmar.

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Background: Acute lower respiratory infection (ALRI) remains the leading cause of death in children worldwide, and viruses have been the major cause of ALRI. In Myanmar, ALRI is associated with high morbidity and mortality in children, and detailed information on ALRI is currently lacking.

Methods: This prospective study investigated the viral aetiologies, clinical manifestations, and outcomes of ALRI in hospitalised children aged 1 month to 12 years at the Yankin Children Hospital, Yangon, Myanmar from May 2017 to April 2019.

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