Long-term effects of surgically corrected menstrual outflow obstruction: A case-control study.

Objective: To enhance evidence-based knowledge on long-term sequalae in patients with surgically corrected obstructing Müllerian anomalies.

Methods: This long-term case-control study included patients with menstrual outflow obstruction due to congenital anomalies of the uterus or vagina, who were at least 18 years old, and for whom 2 years had elapsed since the first surgery at the start of this study. The control group consisted of women without current gynecological problems.

Added value of involving patients in the first step of multidisciplinary guideline development: a qualitative interview study among infertile patients.

Background: Patient involvement in scoping the guideline is emphasized, but published initiatives actively involving patients are generally limited to the writing and reviewing phase.

Objective: To assess patients' added value to the scoping phase of a multidisciplinary guideline on infertility.

Design: Qualitative interview study.

Long-term results of vaginal construction with the use of Frank dilation and a peritoneal graft (Davydov procedure) in patients with Mayer-Rokitansky-Küster syndrome.

Objective: To describe long-term outcomes after nonsurgical and surgical treatment of vaginal agenesis in a cohort of girls and women with Mayer-Rokitansky-Küster (MRK) syndrome.

Design: Retrospective cohort study using a standardized case record form.

Setting: University hospital.

Salpingotomy versus salpingectomy in women with tubal pregnancy (ESEP study): an open-label, multicentre, randomised controlled trial.

Background: Tubal ectopic pregnancy can be surgically treated by salpingectomy, in which the affected Fallopian tube is removed, or salpingotomy, in which the tube is preserved. Despite potentially increased risks of persistent trophoblast and repeat ectopic pregnancy, salpingotomy is often preferred over salpingectomy because the preservation of both tubes is assumed to offer favourable fertility prospects, although little evidence exists to support this assumption. We aimed to assess whether salpingotomy would improve rates of ongoing pregnancy by natural conception compared with salpingectomy.

Galactose-1-phosphate uridyl transferase deficiency is not associated with Müllerian aplasia in Dutch patients.

Study Objective: To study whether a deficiency in galactose-1-phosphate uridyl transferase (GALT) activity of mothers was an explanation for the occurrence of Müllerian aplasia of their daughters.

Design: A case control study.

Setting: The patients were selected from the outpatient clinic of the University Medical Center Nijmegen, and compared with the general population in The Netherlands.

Review of the role of the plasminogen activator system and vascular endothelial growth factor in subfertility.

Objective: To assess the importance of the plasminogen activator (PA) system and vascular endothelial growth factor (VEGF) in subfertility.

Design: Review.

Setting: Two university IVF centers.

The long term outcome of feminizing genital surgery for congenital adrenal hyperplasia: anatomical, functional and cosmetic outcomes, psychosexual development, and satisfaction in adult female patients.

Background: There are only a few reports analyzing the long term outcome of feminizing surgery in females with congenital adrenal hyperplasia (CAH). Such analysis is crucial to evaluate the treatment and to make necessary adjustments.

Study Objectives: To evaluate the adult outcome after feminizing surgery in adult females with salt wasting CAH.