Detectability and acceptability of continuous pulse signals for the MemoPatch(®) device, an electronic skin patch intended to deliver tactile medication reminder signals.

Background: Unintended forgetfulness is the most common cause of medication nonadherence. MemoPatch(®) is an electronic skin patch intended to deliver discreet tactile medication reminder stimuli. This study aimed 1) to evaluate, within an experimental setup, the detectability and acceptability of fifteen continuous bipolar pulse signals; 2) to identify variables, if any, associated with differential perception of the candidate reminder signals; and 3) to collect safety data as reported by subjects or observed by staff.

Detectability and appraisal thresholds of split pulse signals for the MemoPatch™ device, an electronic skin patch intended to deliver tactile medication reminder signals (study TS-104).

Patient non-adherence to prescribed medication regimens is a significant problem and affects clinical treatment outcomes. The MemoPatch™ medical device, currently in development, is an electronic skin patch intended to deliver tactile medication reminder signals. Fifty volunteers completed a laboratory experiment that evaluated the detectability and appraisal thresholds of five split signals; specifically, the current thresholds (in mA) at which a signal was detected (threshold T1), was considered sufficiently detectable to serve as a reminder signal (threshold T2), and became too strong as a reminder signal (threshold T3).

Description, specifications, and ASIC configurations of MEMOPATCH, a transdermal pulse generator medical device to promote patient compliance with medication regimens.

Current methods for improving patients' compliance with their prescribed treatment regimens, especially in those cases where noncompliance is a function of mere forgetfulness, have distinct disadvantages, chief among them their relative obtrusiveness and impact on patient privacy. The MemoPatch concept is a patent-pending electronic reminder system consisting of a dermal patch outfitted with a miniaturized programmable pulse generator (ASIC) that gives patients a perceptible stimulus to the skin. This paper describes the concept, reviews specification, and presents three ASIC-based configurations.