Accuracy of privacy preserving record linkage for real world data in the United States: a systemic review.

Objectives: Examine the accuracy of privacy preserving record linkage (PPRL) matches in real world data (RWD).

Materials And Methods: We conducted a systematic literature review to identify articles evaluating PPRL methods from January 1, 2013 to June 15, 2023. Eligible studies included original research reporting quantitative metrics such as precision and recall in health-related data sources.

Are associations of adulthood overweight and obesity with all-cause mortality, cardiovascular disease, and obesity-related cancer modified by comparative body weight at age 10 years in the UK Biobank study?

Objective: Adults living with overweight or obesity do not represent a single homogenous group in terms of mortality and disease risks. The aim of our study was to evaluate how the associations of adulthood overweight and obesity with mortality and incident disease are modified by (i.e.

Influence of Photoemission Geometry on Timing and Efficiency in 4D Ultrafast Electron Microscopy.

Broader adoption of 4D ultrafast electron microscopy (UEM) for the study of chemical, materials, and quantum systems is being driven by development of new instruments as well as continuous improvement and characterization of existing technologies. Perhaps owing to the still-high barrier to entry, the full range of capabilities of laser-driven 4D UEM instruments has yet to be established, particularly when operated at extremely low beam currents (~fA). Accordingly, with an eye on beam stability, we have conducted particle tracing simulations of unconventional off-axis photoemission geometries in a UEM equipped with a thermionic-emission gun.

Associations of personality trait level and change with mortality risk in 11 longitudinal studies.

People who are higher in conscientiousness, extraversion, and agreeableness and lower in neuroticism tend to live longer. The present research tested the hypothesis that personality trait change in middle and older adulthood would also be associated with mortality risk, above and beyond personality trait level. Personality trait change may causally influence mortality risk through corresponding changes in health behaviors, social processes, and stress experience.

Self-reported diagnoses of dietary allergens and fecundability in a North American cohort.

Study Question: To what extent are self-reported diagnoses of food allergies associated with fecundability, the per-cycle probability of conception?

Summary Answer: Fecundability was not appreciably associated with self-reported food allergy diagnoses, number of food allergies, age at first diagnosis, or time since last allergic reaction.

What Is Known Already: Food allergies are atopic diseases that are characterized by an inappropriate immune response to a normally harmless dietary substance. While some studies have observed associations between atopic disorders and infertility, no study has examined the association between food allergies and fecundability, the per-cycle probability of conception.

Assessment of UK Heavy Goods Vehicle drivers' lifestyle behaviours: a cross-sectional study.

Objective: Heavy Goods Vehicle (HGV) drivers face difficult working conditions, promoting unhealthy lifestyle behaviours which are associated with an elevated prevalence of long-term health conditions.

Methods: 109 drivers across the UK completed an online survey investigating differences in lifestyle behaviours between drivers with (N = 54) and without obesity (N = 55), including differences on work and non-workdays using an exploratory data analysis approach.

Results: Drivers with obesity (49.

Interventions to improve mental health and well-being in care-experienced children and young people aged less than 25: the CHIMES systematic review.

Background: Children and young people with experience of being in care (e.g. foster care, kinship care, residential care or at home with a supervision requirement order) are at higher risk of adverse mental health and well-being outcomes compared to the general population.

The CDK8 kinase module: A novel player in the transcription of translation initiation and ribosomal genes.

Survival following stress is dependent upon reprogramming transcription and translation. Communication between these programs following stress is critical for adaptation but is not clearly understood. The Cdk8 kinase module (CKM) of the Mediator complex modulates the transcriptional response to various stresses.

Assessment of unintentional acute pesticide poisoning among smallholder vegetable farmers in Trinidad and Jamaica.

Poisoning caused by pesticides is widely recognized as a major public health problem among smallholder farmers and rural communities, including in the Caribbean. However, a lack of quality data impedes understanding of the problem and hampers the development of effective strategies for its management. To better understand the prevalence of unintentional acute pesticide poisoning (UAPP) in Trinidad and Tobago and Jamaica and the pesticides and practices involved, we conducted a cross-sectional survey of 197 and 330 vegetable farmers in Trinidad and Jamaica, respectively.

Near-Term Forecasting of Terrestrial Mobile Species Distributions for Adaptive Management Under Extreme Weather Events.

Across the globe, mobile species are key components of ecosystems. Migratory birds and nomadic antelope can have considerable conservation, economic or societal value, while irruptive insects can be major pests and threaten food security. Extreme weather events, which are increasing in frequency and intensity under ongoing climate change, are driving rapid and unforeseen shifts in mobile species distributions.

Why are pharmacy technicians leaving? Factors contributing to turnover intention and strategies for retention.

Background: Pharmacy technicians play a crucial role in the healthcare system to enable pharmacists to focus on clinical services. However, a lack of recognition for their role and contribution leads to high turnover rates.

Objective: To identify the reasons behind pharmacy technicians leaving, or intending to leave, pharmacy practice.

Workforce development in community pharmacies in England: Opportunities and tensions for a private sector provider of NHS services.

Background: The intention to more effectively mobilise and integrate the capabilities of the community pharmacy workforce within primary care is clearly stated within National Health Service (NHS) England policy. The Pharmacy Integration Fund (PhIF) was established in 2016 to support the development of clinical pharmacy practice in a range of primary care settings, including community pharmacy.

Objective: This study sought to determine how PhIF funded learning pathways for post-registration pharmacists and accuracy checking pharmacy technicians enabled community pharmacy workforce transformation, in what circumstances, and why.

A replicate crossover trial on the inter-individual variability of sleep indices in response to acute exercise undertaken by healthy men.

Study Objectives: Using the necessary replicate-crossover design, we investigated whether there is inter-individual variability in home-assessed sleep in response to acute exercise.

Methods: Eighteen healthy men (mean(SD): 26(6) years) completed two identical control (8-h laboratory rest, 08:45-16:45) and two identical exercise (7-h laboratory rest; 1-h laboratory treadmill run [62(7)% peak oxygen uptake], 15:15-16:15) trials in randomised sequences. Wrist-worn actigraphy (MotionWatch 8) measured home-based sleep (total sleep time, actual wake time, sleep latency, sleep efficiency) two nights before (nights 1-2) and three nights after (nights 3-5) the exercise/control day.

Experimental Gas-Phase Removal of OH Radicals in the Presence of NHC(O)H over the 11.7-353 K Range: Implications in the Chemistry of the Interstellar Medium and the Earth's Atmosphere.

Formamide (NHC(O)H) has been observed both in the interstellar medium (ISM), being identified as a potential precursor of prebiotic molecules in space, and in the Earth's atmosphere. In these environments where temperature is very distinct, hydroxyl (OH) radicals may play an important role in the degradation of NHC(O)H. Thus, in this work, we report for the first time the experimental study of the temperature dependence of the gas-phase removal of OH in the presence of NHC(O)H over the 11.

The Relationship Between 10-year Changes in Cognitive Ability and Subsequent Mortality: Findings from the Advanced Cognitive Training for Independent and Vital Elderly (ACTIVE) Trial.

Cognitive ability and cognitive decline are related to mortality in older adults. Cognitive interventions have been found to improve cognitive performance and slow cognitive decline in later life. However, the longitudinal effects of cognitive interventions on mortality in older adults remain unclear.

Med13 is required for efficient P-body recruitment and autophagic degradation of Edc3 following nitrogen starvation.

The Cdk8 kinase module (CKM), a conserved, detachable unit of the Mediator complex, plays a vital role in regulating transcription and communicating stress signals from the nucleus to other organelles. Here, we describe a new transcription-independent role for Med13, a CKM scaffold protein, following nitrogen starvation. In , nitrogen starvation triggers Med13 to translocate to the cytoplasm.

Delineation of the impact on temporal behaviors of off-axis photoemission in an ultrafast electron microscope.

Efforts to push the spatiotemporal imaging-resolution limits of femtosecond laser-driven ultrafast electron microscopes (UEMs) to the combined angstrom-fs range will benefit from stable sources capable of generating high bunch charges. Recent demonstrations of unconventional off-axis photoemitting geometries are promising, but connections to the observed onset of structural dynamics are yet to be established. Here we use the in-situ photoexcitation of coherent phonons to quantify the relative time-of-flight (r-TOF) of photoelectron packets generated from the Ni Wehnelt aperture and from a Ta cathode set-back from the aperture plane.

The Challenges of Measuring Socioeconomic Inequality in Pharmacoepidemiology Studies.

Social conditions like socioeconomic status (SES) are critical sources of health disparities. In pharmacoepidemiology research, our ability to measure SES in retrospective, real world clinical data remains challenged by a lack of patient-reported data. Some broadly accepted concepts can be measured at the individual level, such as income, poverty, and education.