Publications by authors named "Willie Wu"

Combination therapies mediate drug synergy to improve treatment efficacy and convenience, leading to higher levels of compliance. However, there are challenges with their manufacturing as well as reduced flexibility in dosing options. This study reports on the design and characterization of a polypill fabricated through the combination of material jetting and binder jetting for the treatment of hypertension.

View Article and Find Full Text PDF
Article Synopsis
  • Current imaging techniques struggle to differentiate between malignant and benign renal masses, specifically clear cell RCC and oncocytoma, leading to the need for improved diagnostic tools.
  • This study aimed to utilize deep learning with Google TensorFlow™ to create a classifier that can effectively distinguish between ccRCC and ONC using data from four-phase MDCT scans of pathologically confirmed renal masses.
  • The researchers conducted a retrospective analysis, contouring the entire renal mass in each scan phase to extract features necessary for training a machine learning model, exploring various methods to enhance classification accuracy.
View Article and Find Full Text PDF

Hydroxyapatite (HA) scaffolds with a 3-D periodic architecture and multiscale porosity have been fabricated by direct-write assembly. Concentrated HA inks with tailored viscoelastic properties were developed to enable the construction of complex 3-D architectures comprised of self-supporting cylindrical rods in a layer-by-layer patterning sequence. By controlling their lattice constant and sintering conditions, 3-D periodic HA scaffolds were produced with a bimodal pore size distribution.

View Article and Find Full Text PDF