Spinal growth after irradiation for Wilm's tumour.

Between 1960 and 1983, 82 children were treated for Wilm's tumour at our hospital. The secondary effects and changes in the skeleton have been assessed. Radiotherapy was found to cause growth disturbances and osteochondrosis of variable degree, but not osteonecrosis.

[Vertebral changes after irradiation for Wilms' tumor in early childhood. A retrospective interdisciplinary long-term study of 82 children].

82 children with nephroblastomas, who had therapy between 1960 and 1983, underwent continuous follow-up examinations until 1988. 79 children who survived had been treated with nephrectomy followed by radiation therapy (n = 72) and chemotherapy (n = 72). 64 of these patients had a combination of both post-surgical treatments.

[Skeletal age determination in adolescence and the 3d decade of life].

The determination of bone age of hand and wrist focussing primarily on bone centre development is limited to childhood and during this period has diagnostic significance as well as therapeutic consequences. At puberty the fusion of epiphyseal growth plates is more important: it reflects the termination of growth and the biological stage of development. An extension of knowledge can be obtained by correlating age beyond 18 years into the third decade of life.

[Skeletal manifestations of malignant, nonosseous tumors in childhood].

Skeletal involvement in childhood nonosseous tumors can be due to primary involvement, arrosion or metastasis, secondary due to therapy induced alterations or osteomyelitis following diminished immunity. The occurence of bone changes differs widely from those in adults. Neuroblastoma, rhabdomyosarcoma and malignant lymphoma are discussed in detail.

Absence of prognostic significance of skeletal involvement in acute lymphocytic leukemia and non-Hodgkin lymphoma in children.

Over a period of 6 years 88 children with acute lymphocytic leukemia and malignant non-Hodgkin lymphoma were treated according to the West-Berlin protocol. In 72 children skeletal surveys were performed initially and these showed leukemic bone changes in 31 patients. Follow-up was obtained in 70 patients for up to 8 years after diagnosis: 20 of these patients died and of these 8 showed initial skeletal involvement.

[Fold formations in the proximal ureter].

Over a period of thirteen years in 28 children (age 4 weeks to 11 years) mucosal membranes of the proximal ureter were diagnosed by intravenous urography. In 61% of all cases the anomalies were demonstrated within the first year of life. Predominantly boys were affected (75%).

[Roentgen diagnosis of structural changes in the pubic area in children and adolescents. Personal case reports, differential diagnosis and literature review].

Structural changes in the pubic bone often are difficult to interpret. The radiologic appearance is very different. The differentiation between inflammatory and malignant processes is hardly to distinguish.

Condensing osteitis of the clavicle in childhood: a rare sclerotic bone lesion. Review of literature and report of seven patients.

Seven children and adolescents with sclerotic and periosteal alterations of the clavicle are reported, two of them in detail. Malignancies and bacterial inflammatory processes, which were first suspected, could be excluded. Clinical and radiographic features as well as differential diagnosis are discussed, as is the pertinent literature.

[Modern x-ray apparatus for pediatric radiology (Pädiatrix) (author's transl)].

First experiences with the new apparatus "Pädiatrix" in pediatric radiology are reported. The apparatus is especially constructed for babies and children. X-ray pictures can be taken close-up and in distance with the tube above the table.

[Osteonecroses in children with chronic renal diseases before and after kidney transplantation (author's transl)].

From 1969 to 1980 202 children suffering from chronic renal insufficiency underwent treatment in the Children's Hospital of Heidelberg University. In 36 patients kidney transplantation were performed. Two children developed femoral head necroses before transplantation without corticosteroid therapy.

Radiological kidney size in childhood.

Kidney length (KL), renal area and renal parenchymal area were measured on i.v. urograms of 255 children without apparent kidney disease age 0 to 14 years.

Nephrocalcinosis in radiographs, computed tomography, sonography and histology.

In 12 patients with nephrocalcinosis, radiographs were compared with computed tomography, sonography and histology. Computed tomography detects nephrocalcinosis at a very early stage of the disease, gives a better picture of the density and extent of nephrocalcinosis and may detect other findings (e. g.