Angiosarcoma in previously irradiated breast in patient with Li-Fraumeni syndrome. A case report.

Context: Li-Fraumeni syndrome is a rare disease with an autosomal dominant inheritance pattern and high penetrance that defines a 50% chance of developing cancer before the age of 30 years, including cases of breast sarcoma. Patients with this syndrome who require radiotherapy have an increased risk of developing secondary malignancies including angiosarcomas.

Case Report: This was a case report on a female patient with Li-Fraumeni syndrome.