Publications by authors named "Willian Bucker Moraes"
Article Synopsis
- A series of 19 novel eugenol derivatives featuring a 1,2,3-triazole structure were synthesized using a copper(I)-catalyzed reaction, aimed at enhancing antifungal activity.
- Several triazole compounds were tested for their effectiveness against the fungus causing papaya anthracnose, with four compounds showing significant reductions in mycelial growth by over 80%.
- Molecular docking studies revealed how these derivatives bind to the CYP51 enzyme, suggesting that their antifungal properties may stem from blocking substrate access, paving the way for environmentally friendly antifungal agents.
The viability of inoculum was evaluated during the microfermentation process of diseased and healthy pulp-seed masses and on a range of carrier materials: aluminum, cloth, glass, paper, plastic, raffia, and rubber tire. Fungal survival was assessed before the microfermentation (0 h) and every 24 to 96 h by the growth of colonies in potato-dextrose-agar (PDA) and sporulation in seed shells. Colonies of and sporulation on seed shells were observed from seeds not submitted to microfermentation.
View Article and Find Full Text PDFIn agriculture, the control of fungal infections is essential to improve crop quality and productivity. This study describes the preparation and fungicidal activity evaluation of 12 glycerol derivatives bearing 1,2,3-triazole fragments. The derivatives were prepared from glycerol in four steps.
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