In a retrospective study, 54 patients with treatment-resistant major depressive disorder (TRD) completed a free-viewing task in which they had to freely explore pairs of faces (an emotional face (happy or sad) opposite to a neutral face). Attentional bias to emotional faces was calculated for early and sustained attention. We observed a significant negative correlation between depression severity as measured by the 10-item Montgomery-Åsberg Depression Rating Scale (MADRS) and sustained attention to happy faces.
View Article and Find Full Text PDFReproducibility, measurability, and refutability are the foundation of the scientific method applied to empirical work. In the study of animal and human behavior, experimental protocols conducted in the lab are the most reliable means by which scientists can operationalize behaviors using controlled and parameterized setups. However, whether observations in the lab fully generalize in the real world remain legitimately disputed.
View Article and Find Full Text PDFEvidence suggests that psychopathic individuals display difficulties to adapt their behavior in accordance with the demands of the environment and show altered performance monitoring. Studies investigating the error-related negativity (ERN) and the error-positivity (Pe) as electrophysiological markers of error monitoring reported contradictory results for this population. To explain these discrepancies, we hypothesized that psychopathy dimensions influence electrophysiological outcomes.
View Article and Find Full Text PDFThe main goal of the current study was to identify the electrophysiological signatures of the mechanisms involved in the perception of time when expecting positive, neutral or negative stimuli that have equal arousal levels. Participants were asked to compare the duration of time intervals with a 2-sec reference interval. The color of circles marking a given comparison interval signaled the valence of the upcoming stimulus to be presented, each stimulus being drawn from the International Affective Picture System (IAPS).
View Article and Find Full Text PDFBackground: Individuals with psychopathic traits display deficits in emotional processing. A key event-related potential component involved in emotional processing is the late positive potential (LPP). In healthy controls, LPP amplitude is greater in response to negative stimuli than to positive or neutral stimuli.
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