A Comparison of Parent Reports, the Mental Synthesis Evaluation Checklist (MSEC) and the Autism Treatment Evaluation Checklist (ATEC), with the Childhood Autism Rating Scale (CARS).

This study compares two parent reports, the Mental Synthesis Evaluation Checklist (MSEC) and the Autism Treatment Evaluation Checklist (ATEC), with the Childhood Autism Rating Scale (CARS). The ATEC consists of four subscales, as follows: (1) expressive language, (2) sociability, (3) sensory awareness, and (4) health. The MSEC is complementary to the ATEC in measuring complex language comprehension.

Direct kinetic fingerprinting and digital counting of single protein molecules.

The sensitive and accurate quantification of protein biomarkers plays important roles in clinical diagnostics and biomedical research. Sandwich ELISA and its variants accomplish the capture and detection of a target protein via two antibodies that tightly bind at least two distinct epitopes of the same antigen and have been the gold standard for sensitive protein quantitation for decades. However, existing antibody-based assays cannot distinguish between signal arising from specific binding to the protein of interest and nonspecific binding to assay surfaces or matrix components, resulting in significant background signal even in the absence of the analyte.

A Novel Peer-Directed Curriculum to Enhance Medical Ethics Training for Medical Students: A Single-Institution Experience.

Background: The best pedagogical approach to teaching medical ethics is unknown and widely variable across medical school curricula in the United States. Active learning, reflective practice, informal discourse, and peer-led teaching methods have been widely supported as recent advances in medical education. Using a bottom-up teaching approach builds on medical trainees' own moral thinking and emotion to promote awareness and shared decision-making in navigating everyday ethical considerations confronted in the clinical setting.

Concerns of Female Adolescents About Menarche and First Sexual Intercourse: Mixed Methods Analysis of Social Media Questions.

Background: Adolescents use social media for information on medical and social aspects of maturation.

Objective: The aim of this study was to investigate the concerns and information needs of adolescents regarding menarche and first sexual intercourse.

Methods: Questions about menarche or first sexual intercourse were obtained from Yahoo Answers, a community-based social media question-and-answer website.

Creating an active-learning environment in an introductory acoustics course.

Research in physics education has indicated that the traditional lecture-style class is not the most efficient way to teach introductory physical science courses at the university level. Current best teaching practices focus on creating an active-learning environment and emphasize the students' role in the learning process. Several of the recommended techniques have recently been applied to Brigham Young University's introductory acoustics course, which has been taught for more than 40 years.

Evidence based physical activity for school-age youth.

Objectives: To review the effects of physical activity on health and behavior outcomes and develop evidence-based recommendations for physical activity in youth.

Study Design: A systematic literature review identified 850 articles; additional papers were identified by the expert panelists. Articles in the identified outcome areas were reviewed, evaluated and summarized by an expert panelist.

The effect of inharmonic partials on pitch of piano tones.

Piano tones have partials whose frequencies are sharp relative to harmonic values. A listening test was conducted to determine the effect of inharmonicity on pitch for piano tones in the lowest three octaves of a piano. Nine real tones from the lowest three octaves of a piano were analyzed to obtain frequencies, relative amplitudes, and decay rates of their partials.

Screening for Heart Murmurs.

In brief In preparticipation screening, auscultation is a key component of a rapid but thorough cardiovascular exam. A systematic approach allows an examiner to identify the normal murmurs that occur among young athletes as well as the sounds that might signify underlying cardiac pathology. Keeping in mind the factors that influence murmur audibility helps ensure accurate differentiation between normal and pathologic murmurs.

Automated Exercise Blood Pressure Measurements in Children: A Preliminary Study.

This study compared blood pressure and heart rate measurements provided by the Quinton 410 automated exercise monitor with simultaneous auscultatory and electrocardiograph readings during rest, postural change, immediately after each treadmill exercise workload, and during active recovery in a sample of young children (mean age 7.9 yrs). The Quinton 410 provided highly accurate heart rates under all conditions (average mean difference <1.

Does the sympathetic block outlast sensory block: a thermographic evaluation.

A study to evaluate the duration of sympathetic and sensory block in the L2 and L5 dermatome distributions using thermography and pinprick was conducted. Twenty patients received epidural block using 2% lidocaine with epinephrine. Onset and duration of the sensory and sympathetic blocks were determined and compared statistically.