Publications by authors named "William Storm"

During 2012, global detection of a new norovirus (NoV) strain, GII.4 Sydney, raised concerns about its potential effect in the United States. We analyzed data from NoV outbreaks in 5 states and emergency department visits for gastrointestinal illness in 1 state during the 2012-13 season and compared the data with those of previous seasons.

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Background: Caffeine ingestion has been demonstrated to increase physical performance in some situations. This study examined the ability of a commercial energy drink containing caffeine to enhance acceleration tolerance and strength under G load.

Methods: Eight experienced centrifuge subjects completed three separate experimental acceleration exposures following ingestion of 11.

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Background: Spaceflight is associated with increased glucocorticoids and catecholamines, both well-known for their immunosuppressive effects. The objective of this study was to develop a model of spaceflight by using a human centrifuge to reproduce launch and landing G forces along with bed rest to simulate microgravity.

Hypothesis: Acute changes in G forces are causal factors in neuroendocrine and immune changes.

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Background: The hypnotic zolpidem and the hormone melatonin were evaluated and directly compared for their effects on performance when subjects sleeping under their influence were prematurely awakened from daytime sleep.

Method: Non-sleep deprived volunteers (eight men and five women) received single oral doses of 5 or 10 mg melatonin (Mel-5; Mel-10), 10 or 20 mg zolpidem (Zol-10; Zol-20), or placebo immediately before retiring at 13:00. Performance testing and subjective evaluations occurred prior to dosing and following forced awakening at 15:00, 2 h after dosing.

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Study Objectives: The primary objective of this study was to determine whether zaleplon (10 mg) effectively promoted sleep during the daytime in well-rested individuals when compared to placebo. A secondary objective was to see if, while not expected, the use of zaleplon impacted the performance of well-rested individuals upon awakening.

Design: Repeated measures with 2 within-subject factors: drug (placebo/zaleplon) and trial (hourly testing during waking hours).

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The U.S. Department of Defense (DOD) has long pursued applied research concerning fatigue in sustained and continuous military operations.

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Background: Zaleplon appears to be a prime candidate for assisting individuals in obtaining sleep in situations not conducive to rest (i.e., a short period during the day).

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