Case Report: Retinal Infarction Associated with Migraine.

Significance: Retinal migraine and migrainous infarction are distinct clinical entities delineated by the International Headache Society. Presented is a novel case report demonstrating unique optical coherence tomography evidence of retinal ischemia experienced during a migraine with effects across retinal vascular territories. This may represent evidence of migrainous infarction within the retina.

Case Report: Linezolid Optic Neuropathy and Proposed Evidenced-based Screening Recommendation.

Significance: This case illustrates a novel screening protocol for linezolid-induced toxic optic neuropathy.

Purpose: To present a case report and analysis of linezolid-induced optic neuropathies in adult patients to develop screening recommendations.

Case Report: A case report of optic neuropathy from extended use of linezolid illustrates its potential effects on vision.

Clinical presentation of pseudo-abducens palsy.

Purpose: Pseudo-abducens palsy is a neurologic limitation in abduction with an intact abducens nerve. This rare condition can be observed when voluntary eye movements show impairment in lateral gaze, yet the vestibulo-ocular reflex (VOR) demonstrates full abduction. The intact VOR indicates the integrity of the infranuclear abducens nerve, thus suggesting that a pseudo-abducens palsy is likely caused by supranuclear pathology.

Intraocular mantle cell lymphoma of the iris.

Purpose: Non-Hodgkin lymphoma (NHL) is a neoplastic process of the lymphatic system in which tumors develop from lymphocytes. The absence of Reed-Sternberg cells differentiates NHL from Hodgkin lymphoma (HL). Mantle cell lymphoma is a mature B-cell NHL, typically with an aggressive course.

Purtscher's retinopathy associated with acute pancreatitis.

Purpose: Purtscher's retinopathy is a rare condition that is associated with complement-activating systemic diseases such as acute pancreatitis. After pancreatic injury or inflammation, proteases such as trypsin activate the complement system and can potentially cause coagulation and leukoembolization of retinal precapillary arterioles. Specifically, intermediate-sized emboli are sufficiently small enough to pass through larger arteries yet large enough to remain lodged in precapillary arterioles and cause the clinical appearance of Purtscher's retinopathy.

Novel case of ocular neuromyotonia associated with thyroid-related orbitopathy and literature review.

Purpose: To present a novel case of pupillary involvement in ocular neuromyotonia (ONM), a rare ocular syndrome that causes intermittent diplopia because of an abnormal delay in extraocular muscle relaxation and to conduct a literature review.

Methods: A case report is presented to demonstrate clinical characteristics and treatment of ONM. In addition, a literature review is conducted by searching Medline and Embase databases.

Case report: branch retinal vein occlusion and primary antiphospholipid syndrome.

Background: Branch retinal vein occlusion (BRVO) is commonly encountered in older patients with vascular disease. This report presents a case of BRVO in an atypically young patient that precipitated additional testing and a subsequent diagnosis of primary antiphospholipid syndrome. This illustrates a need for a thrombophilic evaluation in atypical patients.

Idiopathic orbital inflammatory syndrome without pain: a case report.

Background: Idiopathic orbital inflammatory syndrome (IOIS) is a collection of primary orbital inflammatory expressions manifested in a variety of clinical presentations. Because the process is idiopathic, it lacks association with neoplastic, infectious, or systemic immunologic and inflammatory diseases. Therefore, an extensive analysis is required to exclude secondary etiologies of orbital inflammation.

Adenocarcinoma metastasis causing discrete extraocular muscle enlargement.

Background: Discrete extraocular muscle (EOM) metastasis is rarely reported. Clinical signs and symptoms of EOM metastasis can often be indistinguishable from primary idiopathic orbital myositis, posing a significant clinical challenge.

Case Report: A case of a 61-year-old man with acute-onset unilateral periorbital pain and diplopia is presented.

Diabetic papillopathy and its relation to optic nerve ischemia.

Purpose: This presentation exhibits a case report and review of multiple reported cases of hyperemic optic disc swelling in patients with diabetes. After excluding all other known causes of optic nerve insult, this pathology has typically been labeled as diabetic papillopathy.

Case Report: We offer a case of a 65-year-old veteran with unilateral hyperemic optic disc swelling, presenting with minimal optic nerve dysfunction.