Towards cross-application model-agnostic federated cohort discovery.

Objectives: To demonstrate that 2 popular cohort discovery tools, Leaf and the Shared Health Research Information Network (SHRINE), are readily interoperable. Specifically, we adapted Leaf to interoperate and function as a node in a federated data network that uses SHRINE and dynamically generate queries for heterogeneous data models.

Materials And Methods: SHRINE queries are designed to run on the Informatics for Integrating Biology & the Bedside (i2b2) data model.

SHRINE: enabling nationally scalable multi-site disease studies.

Results of medical research studies are often contradictory or cannot be reproduced. One reason is that there may not be enough patient subjects available for observation for a long enough time period. Another reason is that patient populations may vary considerably with respect to geographic and demographic boundaries thus limiting how broadly the results apply.

Service-oriented architecture for pediatric immunization decision support.

We integrate a personally-controlled health record (PCHR) with a Department of Public Health (DPH) immunization registry and clinical decision support (CDS) tool, creating an immunization information system using a service-oriented architecture (SOA). This SOA enables the DPH, a trusted authority, to provide CDS to both clinicians and patients/parents.

Evaluation of influenza prevention in the workplace using a personally controlled health record: randomized controlled trial.

Background: Personally controlled health records (PCHRs) are accessible over the Internet and allow individuals to maintain and manage a secure copy of their medical data. These records provide a new opportunity to provide customized health recommendations to individuals based on their record content. Health promotion programs using PCHRs can potentially be used in a variety of settings and target a large range of health issues.

Indivo: a personally controlled health record for health information exchange and communication.

Background: Personally controlled health records (PCHRs), a subset of personal health records (PHRs), enable a patient to assemble, maintain and manage a secure copy of his or her medical data. Indivo (formerly PING) is an open source, open standards PCHR with an open application programming interface (API).

Results: We describe how the PCHR platform can provide standard building blocks for networked PHR applications.

Integration of the personally controlled electronic medical record into regional inter-regional data exchanges: a national demonstration.

We present the approach taken in a Massachusetts-based national demonstration project to integrate the PING personally controlled health record (PCHR) with the MA-SHARE network, the state-wide inter-organizational data exchange. We describe how we have created a patient-controlled gateway to the network, and how PCHRs have become a first class data source in the network.

The PING personally controlled electronic medical record system: technical architecture.

Despite progress in creating standardized clinical data models and interapplication protocols, the goal of creating a lifelong health care record remains mired in the pragmatics of interinstitutional competition, concerns about privacy and unnecessary disclosure, and the lack of a nationwide system for authenticating and authorizing access to medical information. The authors describe the architecture of a personally controlled health care record system, PING, that is not institutionally bound, is a free and open source, and meets the policy requirements that the authors have previously identified for health care delivery and population-wide research.

Kinematics of the human knee using an open chain cadaver model.

There continues to be controversy about the kinematics of the human knee. This study used seven knees from cadavers moved by pulling on the quadriceps tendon in an open chain fashion using video motion analysis to determine the instantaneous helical axis of movement. Computed tomography scans of the specimens allowed the axes to be related to condyles.