A simple method to visualize pre-mRNA splicing with the naked eye using a genetically encoded visual splicing reporter.

A genetically encoded splicing reporter allows naked-eye visualization of pre-mRNA splicing and requires no expensive equipment or substrate.

The future of medicare hospital payment.

The combination of health care cost growth exceeding general inflation and the swelling of beneficiary rolls with baby boomers will create fiscal pressure for Medicare. Despite dramatic declines in the growth of hospital costs following the introduction of Medicare's prospective payment system (PPS), the growth in Medicare hospital spending per beneficiary has been close to three times the overall rate of inflation since 2000. This paper examines issues related to Medicare's using its pricing policies to more aggressively pursue hospital cost containment.

Five- and Six-Coordinate Group 4 Compounds Stabilized by beta-Ketiminate and Diketiminate Ligands: Syntheses and Comparisons between Solid-State and Solution Structures.

The preparation and reaction chemistry of beta-diketiminate titanium and zirconium complexes is described. Amine elimination reactions work well for introducing Tolnacnac or Tolnacac to the metal centers (TolnacnacH = 2-(p-tolylamino)-4-(p-tolylimino)-2-pentene; TolnacacH = 4-p-toluidinopent-3-en-2-one). In certain cases, the iminium salt of the diketimine can be used to circumvent the unfavorable reaction kinetics.