Publications by authors named "William Sanabria Simoes"

Among the spectrum of gliomas, glioblastoma stands out as the most aggressive brain tumor affecting the central nervous system. In addressing this urgent medical challenge, exploring therapeutic alternatives becomes imperative to enhance the patient's prognosis. In this regard, Butia odorata (BO) fruit emerges as a promising candidate due to its array of bioactive compounds, including flavonoids, phenolic acids, and carotenoids, known for their antioxidant, anti-inflammatory, and antitumor properties.

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: Type 2 Diabetes Mellitus (T2DM) is characterized by hyperglycemia, increased risk of cardiovascular diseases, and oxidative imbalances. This study aimed to investigate the impact of dietary supplementations with 'Arinto' grape pomace flour (GPF) (WGPF) and 'Touriga Nacional' GPF (RGPF) in an animal model of T2DM. : T2DM was induced by a high-fat diet (HFD) for 28 days and a single dose of streptozotocin (STZ) (35 mg/kg) on the 21st day.

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This study explores the therapeutic benefits of tannic acid (TnA) in an experimental protocol of chronic hypermethioninemia in rats. Rats were categorized into four groups: Group I - control, Group II - TnA 30 mg/kg, Group III - methionine (Met) 0.2-0.

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Article Synopsis
  • A study tested how a special plant extract affects female mice that were made to feel depressed with a substance called LPS.
  • The extract helped reduce signs of depression and protected the brain from harmful chemicals that LPS caused.
  • The findings suggest that this plant extract might be useful for helping people with serious depression.
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