Determination of dose enhancement caused by AuNPs with Xoft Axxent Electronic (eBx™) and conventional brachytherapy: in vitro study.

Purpose: The purpose of this study was to determine dose enhancement (DE) and the possible clinical benefits associated with the inclusion of gold nanoparticles (AuNPs) in cancer cells irradiated by either an Ir brachytherapy source or a Xoft Axxent Electronic (eBx™) Brachytherapy.

Patients And Methods: Brachytherapy DE caused by AuNPs is investigated using two methods, namely Ir and eBx™ Brachytherapy. The second method, which was recently introduced clinically, operates at ~50 kV, which is also the optimal beam energy for DE.