Green sample preparation of medicinal herbs in closed digester block for elemental determination by ICP OES.

This work presents a simple, cost-effective, and environmentally friendly digestion method employing inductively coupled plasma optical emission spectrometry (ICP OES) for the determination of As, Ca, Cd, Cr, Cu, Fe, K, Mg, Mn, Na, P, Pb, Sr, and Zn in medicinal herbs. A fractional factorial design uses a multivariate strategy to optimize the experimental parameters. At 180 ºC and 120 min of sample digestion, the optimal condition for a closed block digester was achieved with a mixture consisting of 1.