Publications by authors named "William Pierre"
Article Synopsis
- The study introduces a compact 3D diffractive microscope designed for long-term observation of developing organisms within a cell incubator without moving parts, making it easy to use with standard cell culture containers.
- The microscope images large specimens (over 100µ in size) at subcellular resolution by reconstructing optical properties using intensity-only images taken from various angles with an LED array, aided by a deep-learning neural network.
- This technology was successfully applied to time-lapse 3D imaging of preimplantation mouse embryos over six days, allowing for detailed insights into embryo development and viability without the need for labels.
