Long-term compliance with follow-up after treatment for cervical intra-epithelial neoplasia.

Objective: To assess the level of compliance with follow-up over time after treatment for preinvasive and Stage Ia1 lesions of the cervix. To compare the average interval between visits with the interval prescribed by protocol and to evaluate the use of this difference as a measure of compliance.

Design: Retrospective observational study.

Advances in the imaging and detection of cervical intra-epithelial neoplasia.

Screening for preinvasive disease of the cervix, and detecting and mapping the lesions for treatment, are fundamental to programs for the prevention of cervical cancer. These will become even more important in women vaccinated against humanpapilloma viruses 16 and 18. Biophysical imaging technologies have considerable potential advantages in both screening for and mapping the lesions.

Long-term risk of invasive cervical cancer after treatment of squamous cervical intraepithelial neoplasia.

Invasive cancer of the cervix after treatment for cervical intraepithelial neoplasia (CIN) is becoming more important, as screening reduces the incidence of invasive disease. The rate of invasive cervical or vaginal cancer following treatment for CIN in UK remains elevated for at least 8 years. The aim of our study was to determine from international data how long this rate remains elevated and whether the rate of invasive disease reflects the rate of posttreatment CIN.