Publications by authors named "William M Pardridge"
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Synopsis of recent research by authors named "William M Pardridge"
- William M Pardridge's research primarily focuses on innovative strategies for drug delivery across the blood-brain barrier (BBB), addressing challenges related to the treatment of neurological diseases through receptor-mediated transport and the development of biologics.
- Recent studies highlight potential treatments for conditions like Parkinson's disease and CLN1 disease, utilizing biologics such as neurotrophins and lysosomal enzymes that can effectively penetrate the BBB.
- Pardridge's work also encompasses the development of mathematical models to predict the transport kinetics of monoclonal antibodies targeting the insulin and transferrin receptors, advancing the understanding of biologics' delivery mechanisms in the brain.
