The separation of several organophosphate pesticides on immobilized polysaccharide chiral stationary phases.

While not initially a focus or priority, in recent decades, an emphasis has been placed on the activity of individual enantiomers of widely used pesticides. Of particular note are organophosphorus-based pesticides like fenamiphos and profenofos, as examples. This work explores the enantioselective high-performance liquid chromatography (HPLC) separations of seven such organophosphorus pesticides (OP's) on the library of immobilized polysaccharide-based chiral stationary phases (CSPs) with normal phase hexane/alcohol mixtures.

Liquid chromatographic separation of the enantiomers of trans-chlordane, cis-chlordane, heptachlor, heptachlor epoxide and alpha-hexachlorocyclohexane with application to small-scale preparative separation.

Analytical high-performance liquid chromatographic separations of the individual enantiomers of five polychlorinated compounds were obtained on polysaccharide stereoselective HPLC columns. The enantiomers of the pesticides trans-chlordane, cis-chlordane and heptachlor were separated on CHIRALCEL OD using a hexane mobile phase. The enantiomers of the heptachlor metabolite, heptachlor epoxide, were separated on CHIRALPAK AD using a methanol mobile phase.