Synopsis of recent research by authors named "William Klunk"
- William Klunk's recent research focuses on identifying and validating blood-based biomarkers for Alzheimer's disease (AD), emphasizing the evaluation of neuroinflammation, cerebrovascular damage, and synaptic dysfunction through advanced multi-analyte proteomic techniques.
- He has explored the timelines of amyloid and tau PET imaging in individuals with Down syndrome, addressing their increased risk for AD and how these biomarkers correlate with disease progression.
- Klunk's studies also assess methodological advancements in biomarker collection and analysis, including the use of protease inhibitors to enhance biomarker stability, and the effects of genetic mutations on disease pathology, contributing to a better understanding of AD and its related disorders.