Quantum chemistry is a promising application for noisy intermediate-scale quantum (NISQ) devices. However, quantum computers have thus far not succeeded in providing solutions to problems of real scientific significance, with algorithmic advances being necessary to fully utilize even the modest NISQ machines available today. We discuss a method of ground state energy estimation predicated on a partitioning of the molecular Hamiltonian into two parts: one that is and can be solved classically, supplemented by a component that yields quantum corrections obtained via a Variational Quantum Eigensolver (VQE) routine.
View Article and Find Full Text PDFThere is no such thing as "zero-COVID." As the Omicron variant spreads to China's capital city, Beijing, the question is not if, but when and how, China will begin to "live with COVID-19" rather than continue to impose endless lockdowns. The problem is that under China's stifling political climate, this notion cannot be uttered, let alone debated.
View Article and Find Full Text PDFHybrid quantum-classical variational algorithms such as the variational quantum eigensolver (VQE) and the quantum approximate optimization algorithm (QAOA) are promising applications for noisy, intermediate-scale quantum computers. Both VQE and QAOA variationally extremize the expectation value of a Hamiltonian. All work to date on VQE and QAOA has been limited to Pauli representations of Hamiltonians.
View Article and Find Full Text PDFWe present a quantum algorithm for simulation of quantum field theory in the light-front formulation and demonstrate how existing quantum devices can be used to study the structure of bound states in relativistic nuclear physics. Specifically, we apply the Variational Quantum Eigensolver algorithm to find the ground state of the light-front Hamiltonian obtained within the Basis Light-Front Quantization (BLFQ) framework. The BLFQ formulation of quantum field theory allows one to readily import techniques developed for digital quantum simulation of quantum chemistry.
View Article and Find Full Text PDFPerioral cosmesis is an important component of facial aesthetics. The perioral region is prone to revealing signs of aging due to repetitive movements and various environmental factors. While it is well established that perioral aesthetics can be effectively treated with hyaluronic acid dermal filler, there is limited published data available on injection techniques specifically designed for perioral rejuvenation.
View Article and Find Full Text PDFPhys Rev Lett
November 2019
Contextuality is an indicator of nonclassicality, and a resource for various quantum procedures. In this Letter, we use contextuality to evaluate the variational quantum eigensolver (VQE), one of the most promising tools for near-term quantum simulation. We present an efficiently computable test to determine whether or not the objective function for a VQE procedure is contextual.
View Article and Find Full Text PDFBackground: Laser tattoo removal using quality switched technology is widely accepted as the standard of care. Determining the risk of hypertrophic scarring and keloid formation more precisely delineates the safety of this procedure and improves patient education regarding the risk of scarring.
Objective: To investigate the incidence of hypertrophic scarring and keloids in a large patient population following treatment with a Q-switched neodymium-doped:yttrium-aluminum-garnet laser.
Most protozoans that have been cultivated recently from high salinity waters appear to be obligate halophiles. Phylogenetic analyses indicate that these species mostly represent independent lineages. Here, we report the cultivation, morphological characterization, and phylogenetic analysis of two strains (XLG1 and HLM-8) of a new extremely halotolerant heterolobosean amoeboflagellate.
View Article and Find Full Text PDFJ Clin Aesthet Dermatol
July 2013
While placement of ink into the skin is a long-standing tradition, patients are now seeking tattoo removal on a more frequent basis. Once considered acceptable removal options, tattoo ink removal via physical destruction included dermabrasion, chemical destruction, salabrasion, thermal destruction, and cryotherapy. Now these options are used extremely infrequently.
View Article and Find Full Text PDFBackground: Tattoo removal using Q-switched lasers is well established in the medical literature, but it is not clear how tattoos on mucosal membranes should be treated because of their infrequent presentation.
Objective: To report successful cosmetic tattoo removal using Q-switched laser irradiation on the oral mucosal surface.
Materials And Methods: Three men with cosmetic tattoos on the orolabial mucosa of the lower lip sought permanent removal.
Background: Ultraviolet radiation (UVR) contributes to the vast majority of nonmelanoma skin cancer (NMSC). As the incidence of NMSC continues to rise, topical therapies will be used with increasing frequency. Topical therapies may benefit high-risk surgical candidates as an alternative treatment modality and may improve overall cosmesis.
View Article and Find Full Text PDFJ Clin Aesthet Dermatol
January 2010
Widely considered the gold standard treatment option for tattoo removal, the use of Q-switched lasers may very rarely result in the formation of large bulla. While very disconcerting to patients, these lesions are easily managed and, with proper care, heal quickly with no long-term consequences. The authors present three cases of patients who had bullous reactions shortly after receiving Q-switched laser treatment of tattoo ink.
View Article and Find Full Text PDFIt is widely accepted that Q-switched lasers are the gold-standard treatment for the resolution of unwanted tattoo ink. Although much safer than other tattoo removal modalities, the treatment of tattoo ink with Q-switched devices may be associated with long-term adverse effects including undesired pigmentary alterations such as tattoo ink darkening. Darkening of tattoo ink is most often reported in cosmetic, flesh-toned, white, peach, and pink tattoos.
View Article and Find Full Text PDFTattoo artists use many compounds to create tattoo pigment and several allergic reactions can occur as a result of these additives. The compositions of many inks have been identified; however, as new mixtures are created it becomes difficult to identify the specific ingredients in a particular ink. Allergic reactions to a particular pigment can manifest in several ways including allergic contact dermatitis and photoallergic dermatitis.
View Article and Find Full Text PDFJ Clin Aesthet Dermatol
March 2009
Background: As tattoos have become increasingly popular in the Western world, tattoo-removal requests have also increased, as patients' personal identities advance. Laser tattoo removal is the current treatment of choice given its safety and efficacy. However, due to varying types of tattoos, it has been difficult to quantify the number of laser treatments required with certainty when discussing laser tattoo removal with our patients.
View Article and Find Full Text PDFCalciphylaxis is a rare disorder characterized by microcalcification of small- and medium-sized blood vessels causing cutaneous and soft tissue necrosis. Patients usually present with painful, violaceous skin discoloration in a livedo reticularis pattern. We present a case of a 59-year-old woman with end-stage renal disease (ESRD) who manifested signs and symptoms of inflammatory breast cancer.
View Article and Find Full Text PDFFour critically ill neonates and two small children have undergone a total of nine postoperative cardiac catheterizations involving mechanical thrombolysis and early post-procedure abciximab for significant venous thrombus obstruction. Bacterial infection was associated in five patients and suspected in a sixth. These procedures achieved near normal venous flow pattern and subsequent long-term seemingly normal central veins in the three survivors (by ultrasound in two patients and by autopsy in the other who subsequently died of sepsis).
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