Considerations for selecting the correct animal model for dermal wound-healing studies.

An array of animal models has been described to elucidate wound-healing processes and access the impact of various therapies on healing. However, which model to use for different applications may not be immediately apparent. This article will highlight less frequently used animal models so as to illustrate their utility and increase their use.

Considerations for determining if a natural product is an effective wound-healing agent.

Many research groups are examining natural products for their vulnerary activity. On the basis of the countless years of folklore and clinical observations, these preparations are being fractionated and applied to wounds in a variety of animal species. Despite this work, the number of agents that have documented ability to enhance wound healing is minimal.

Management of infiltration injury in neonates using duoderm hydroactive gel.

Neonates are at increased risk of injury from infiltration of intravenous fluids because of small vessel size and immature skin structure. Until recently, hyaluronidase injection was used to prevent tissue injury following the infiltration of intravenous solutions in neonates. The production of hyaluronidase injection was discontinued in 2001.