Publications by authors named "William J Beasley"

Contour propagation is an essential component of adaptive radiotherapy, but current contour propagation algorithms are not yet sufficiently accurate to be used without manual supervision. Manual review of propagated contours is time-consuming, making routine implementation of real-time adaptive radiotherapy unrealistic. Automated methods of monitoring the performance of contour propagation algorithms are therefore required.

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Contouring structures in the head and neck is time-consuming, and automatic seg-mentation is an important part of an adaptive radiotherapy workflow. Geometric accuracy of automatic segmentation algorithms has been widely reported, but there is no consensus as to which metrics provide clinically meaningful results. This study investigated whether geometric accuracy (as quantified by several commonly used metrics) was associated with dosimetric differences for the parotid and larynx, comparing automatically generated contours against manually drawn ground truth contours.

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Article Synopsis
  • Infractional anatomical changes can affect how well step-and-shoot IMRT and VMAT deliver radiation doses, but their impact on head and neck cancer has not been thoroughly studied.
  • A study involving 10 patients undergoing repeat CT scans analyzed and compared the effectiveness of step-and-shoot IMRT versus VMAT in dose delivery and target coverage.
  • Results showed that although both techniques had notable dosimetric changes following the second CT scan, there were no significant differences in plan robustness between IMRT and VMAT for the patients in this study.
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