Publications by authors named "William Hua"
Article Synopsis
- Treatment for alcohol use disorder (AUD) is important for improving health outcomes in patients with alcohol-associated cirrhosis, yet it remains underutilized, especially among socioeconomically disadvantaged groups.
- A study of 196 diverse patients revealed that 67% had ever utilized AUD treatment, while only 32% accessed treatment in the last year; younger patients and those with worse mental health symptoms were more likely to seek treatment.
- Factors such as older age and better liver disease quality of life were associated with lower treatment utilization, while those with significant anxiety or depression tended to seek treatment more frequently.
Article Synopsis
- Alcohol use is common among patients with chronic liver disease (CLD), and this study examined factors that affect their motivation to reduce drinking.
- The study involved 121 participants from safety-net hospitals and Veterans Affairs systems, assessing their mental health, alcohol use, and motivation to decrease drinking through various questionnaires.
- Results showed that depression and severity of alcohol problems were linked to higher motivation, while the treatment site impacted their importance score, indicating these factors should guide future interventions in hepatology care.
Article Synopsis
- - Veterans Health Administration provides tailored care for over 30,000 Veterans living with HIV, addressing their unique cultural backgrounds and multiple health challenges, including stigma and mental health issues.
- - The Infectious Disease Care and Resilience (IDCaRe) team at San Francisco VA developed a five-step model to enhance care for Veterans facing significant healthcare challenges, applying existing research and culturally sensitive practices.
- - Initial results from three case studies indicate that the IDCaRe model could effectively improve health outcomes for Veterans with complex HIV-related needs, highlighting its potential for broader application in the future.
Grief responses range from minimal changes in functioning to debilitating, prolonged, complicated grief. The objective of the current study was to clarify the relationship between maladaptive personality characteristics, coping and situational factors associated with symptoms of complicated grief and health difficulties among bereaved individuals who had lost a loved one within the past six months to two years ( = 304; 59% male; age = 33.49, = 9.
View Article and Find Full Text PDFIt has become consensus that mild cognitive impairment (MCI), one of the early symptoms onset of Alzheimer's disease (AD), may appear 10 or more years after the emergence of neuropathological abnormalities. Therefore, understanding the progression of AD biomarkers and uncovering when brain alterations begin in the preclinical stage, while patients are still cognitively normal, are crucial for effective early detection and therapeutic development. In this paper, we develop a Bayesian semiparametric framework that jointly models the longitudinal trajectory of the AD biomarker with a changepoint relative to the occurrence of symptoms onset, which is subject to left truncation and right censoring, in a heterogeneous population.
View Article and Find Full Text PDFBackground: Chronic pain and opioid use disorder (OUD) individually represent a risk to health and well-being. Concerningly, there is evidence that they are frequently co-morbid. While few treatments exist that simultaneously target both conditions, preliminary work has supported the feasibility of an integrated behavioral treatment targeting pain interference and opioid misuse.
View Article and Find Full Text PDFAllogeneic stem cell transplantation (allo-SCT) is now part of standard of care for acute leukemia (AL). To reduce toxicity of the pre-transplant conditioning regimen, intravenous busulfan is usually used as a preparative regimen for AL patients undergoing allo-SCT. Systemic busulfan exposure, characterized by the area under the plasma concentration versus time curve (AUC), is strongly associated with clinical outcome.
View Article and Find Full Text PDFBackground: The rates of obesity and substance abuse are high among US veterans.
Objective: To examine weight loss and substance abuse rates following bariatric surgery in veterans with a history of substance abuse (SA).
Methods: A prospective database of consecutive bariatric operations was reviewed.