[Semantic analysis of online conversations on lung cancer: The WE-Lung research].

Introduction: Today, patients with lung cancer and their relatives can easily search information on the Internet and express themselves online.

Methods: Within this web-ethnographic research, we found, based on 246 search terms related to lung cancer, and collected, a sample of 136 online conversations that were published between January 2004 and September 2018, including 1220 messages by 762 authors.

Results: The authors of messages, many of them close relatives of patients (35%), share their experience (34%).

FRESC: French Real world Extensive stage SCLC Cohorts: A retrospective study on patient characteristics and treatment strategy based on KBP-2010.

Objectives: FRESC reanalyzed extensive-stage small-cell lung cancer (ES-SCLC) patient data from the French KBP-2010 cohort to describe the characteristics and therapeutic management of ES-SCLC and provide real-world estimates of survival.

Methods: A target population of first line (1L) ES-SCLC was identified at initial diagnosis in KBP-2010 (KBP population, N = 796). A KBP-2010 subpopulation was defined as patients who also met the IMpower133 clinicaltrial PS ≤ 1 inclusion criteria (KBP-PS_0/1 population, N = 394).

A comparison of marginal fit between press-fabricated and CAD/CAM lithium disilicate crowns.

The purpose of this study was to compare the marginal fit of press-fabricated lithium disilicate crowns with that of computer-aided design/computer-aided manufacturing (CAD/CAM) lithium disilicate crowns to determine if the fabrication method has an influence on marginal fit. The marginal fit of 25 pressed and 25 CAD/CAM crowns was measured using the replica technique. The sites measured were the mesial, distal, facial, and lingual margins.

Placement and replacement rates of amalgam and composite restorations on posterior teeth in a military population.

Objective: Replacement rates of direct dental restorations have been reported to be 37% to 70%, occupying a large proportion of a general dentist's time. Variations in the rate of initial placement and replacement of direct dental restorations may be associated with material placed (amalgam or composite), age, caries risk of the patient, and other factors. The purpose of this research was to clarify where the majority of patient care time is spent as a restorative Army dentist regarding either the initial placement or replacement of failed restorations; and how the location, caries risk, and material used (amalgam or composite) affects replacement rates.

Microcomputed tomographic comparison of posterior composite resin restorative techniques: sonicated bulk fill versus incremental fill.

Sonication technology has recently been touted to decrease composite viscosity during delivery and may allow better cavity preparation adaptation and minimize voids. The purpose of this investigation was to evaluate the difference between conventional, hand-placed, incremental application of a standard hybrid resin-based composite (RBC) and sonicated application of a bulk-fill RBC in box-type and cylindrical cavity preparations. Experimental restorations were fabricated using molds of box-type or cylindrical preparations.

Effectiveness of a Dental Unit Waterline Treatment Protocol With A-Dec ICX and Citrisil Disinfectants.

This study evaluated the effectiveness of a Dental Unit Waterline disinfection protocol utilizing two waterline disinfectant tablets in a dental treatment clinic. The water effluent from 47 dental treatment units was sampled to determine bacterial load. Four dental treatment units were shocked with the multivalent Sterilex Ultra liquid biocide, followed by a 5-week course of routine disinfection using either the A-dec ICX or Citrisil effervescing tablets.