Publications by authors named "William E Nwachukwu"

Article Synopsis
  • Since 2017, yellow fever has been a significant health concern in Nigeria, with coordinated response efforts led by the Nigeria Centre for Disease Control and supported by the World Health Organization, emphasizing the need to identify mosquito vectors involved in transmission.
  • Over a period from 2017 to 2020, researchers collected various stages of mosquitoes in sixteen states, using advanced techniques to identify species and detect arboviruses.
  • The study found that many states harbored virus-infected mosquitoes, particularly the yellow fever virus, posing a considerable risk of transmission, with certain regions showing higher infection rates and mosquito populations surpassing typical thresholds for disease spread.
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Article Synopsis
  • - A national study in Nigeria assessed schistosomiasis seroprevalence among children aged 0 to 14 using blood samples from the 2018 HIV/AIDS Indicator and Impact Survey, finding an overall seroprevalence of 17.2%.
  • - The analysis revealed that higher seroprevalence was linked to being a boy, living in rural areas, and owning animals, while access to improved sanitation and clean drinking water significantly reduced the odds of being seropositive.
  • - The findings underscore the need for targeted prevention strategies, especially for young children and those with animal exposure, to effectively control schistosomiasis in Nigeria.
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Article Synopsis
  • * This study utilized metagenomic sequencing to analyze mosquito samples collected from Yellow fever outbreaks in Nigeria between 2017 and 2020, focusing on Aedes and Anopheles species.
  • * A total of seven distinct viruses were identified, expanding the understanding of insect-specific viruses (ISVs) and their potential link to pathogenic viruses, demonstrating the effectiveness of advanced sequencing technology in virology research.
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Yellow fever (YF) is an acute viral hemorrhagic disease caused by the YF virus (arbovirus) which continues to cause severe morbidity and mortality in Africa. A case of YF was confirmed in Nigeria on the 12th of September 2017, 21 years after the last confirmed case. The patient belongs to a nomadic population with a history of low YF vaccination uptake, in the Ifelodun Local Government Area (LGA) of Kwara State, Nigeria.

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