Assessing the effect of the Surviving Sepsis Campaign treatment guidelines on clinical outcomes in a community hospital.

Background: Bundles yield a reduction in mortality in patients with sepsis, but the majority of the data is from large academic centers. The ability of a community hospital to implement a sepsis bundle successfully, however, has not been investigated.

Objective: To examine the effect of a collaborative 2-part sepsis bundle on clinical outcomes and mortality at a community hospital.

Fatal type 3 adenoviral pneumonia in immunocompetent adult identical twins.

We describe adult twin sisters who developed severe adenoviral pneumonia with relative leukopenia, progressive focal infiltrates, shock, and hypoxia. Potential determinants of severe adenoviral disease are discussed.